Pyroptosis-related long-noncoding RNAs (PRlncRNAs) play an important role in cancer progression. However, their role in lung squamous cell carcinoma (LUSC) is unclear. A risk model was constructed using the least absolute shrinkage and selection operator (LASSO) Cox regression analysis based on ...
Osteosarcoma is a highly malignant tumor, with very high disability and fatality rates. However, the overall prognosis is not optimistic. Pyroptosis is a newly discovered cell death modality accompanied by inflammation, which is closely related to varieties of cancers. In this study, the RNA-seq d...
Pyroptosis is a kind of programmed cell death triggered by the inflammasome. Growing evidence has revealed the crucial utility of pyroptosis in tumors. However, the potential mechanism of pyroptosis in clear cell renal cell carcinoma (ccRCC) is still unc
if i ed 34 pyroptosis-related dif f erentially expressed genes (DEGs) in glioma. By cluster-ing these DEGs, all glioma cases can be divided into two clusters. Survival analysis showed that the overall survival time of Cluster 1 was signif i cantly higher than that of Cluster 2. Using th...
A correlation was established between the pyroptosis-related LncRNA signature and the TIME, underlying the mutual effect between pyroptosis and the immune responses implicated in breast cancer. The findings in this work underline the critical role exerted by pyroptosis in breast cancer, providing new ...
pyroptosisSMAD4Lung squamous cell carcinoma (LUSC) is one of the most common malignant tumors of the respiratory. Pyroptosis plays an essential role in cancer, but there is limited research investigating pyroptosis in LUSC. In this study, pyroptosis鈥恟elated genes were observed to have extensive ...
In this study, using bioinformatics and a literature-based pyroptosis database, we discovered pyroptosis-related genes that act in NASH. The results showed that NASH had a significant expression of PLCG1, a gene associated with pyroptosis. In addition, PLCG1-based diagnostic models have significan...
Head and neck squamous cell carcinoma (HNSCC) is a major threat to public health. Pyroptosis is a form of inflammatory programmed cell death that is still incompletely understood. The role of pyroptotic cell death in HNSCC remains to be fully defined. As
Figure 4Venn diagrams of the differentially expressed genes (DEGs) and pyroptosis-related genes (PRGs). The pink circles represent the DEGs between PIHs and IIHs, and the blue circles represent the genes related to pyroptosis. Fourteen genes that were common to the IH regression-associated DEGs ...
Pyroptosis, an emerging type of programmed cell death. The mechanisms of pyroptosis mainly include inflammasome-activated pyroptosis and non-inflammasome-activated pyroptosis. Multiple prognostic scoring systems that utilize pyroptosis-related gene expression have been validated as effective predictors of patient...