PYCR1-IN-1 (compound 4) 是一种吡咯啉-5-羧酸还原酶 1 (PYCR1) 抑制剂,IC50 为 8.8 µM。PYCR1-IN-1 具有抗癌活性。 详细介绍 产品活性:PYCR1-IN-1 (compound 4) 是一种吡咯啉-5-羧酸还原酶 1 (PYCR1) 抑制剂,IC50 为 8.8 µM。PYCR1-IN-1 具有抗癌活性。 品牌介绍: MCE (MedChem...
PYCR1-IN-1 (compound 4) 是一种吡咯啉-5-羧酸还原酶 1 (PYCR1) 抑制剂,IC50 为 8.8 µM。PYCR1-IN-1 具有抗癌活性。 详细介绍 产品活性:PYCR1-IN-1 (compound 4) 是一种吡咯啉-5-羧酸还原酶 1 (PYCR1) 抑制剂,IC50 为 8.8 µM。PYCR1-IN-1 具有抗癌活性。
Cat No.66510-1-Ig 浓度:1800 ug/ml 库存:现货 点击咨询售前客服 点击咨询售后客服 PYCR1,also named as P5CR1, belongs to the pyrroline-5-carboxylate reductase family. It is a housekeeping enzyme that catalyzes the last step in proline biosynthesis. PYCR1 can utilize both NAD and NADP, but ha...
66510-1-PBS targets PYCR1 as part of a matched antibody pair: MP50786-1: 66510-2-PBS capture and 66510-1-PBS detection (validated in Cytometric bead array) Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready ...
图:1/3 PYCR1 Antibody (PA5-30141) in ICC/IF PYCR1 Polyclonal Antibody detects PYCR1 protein at mitochondria by immunofluorescent analysis. Sample: HeLa cells were fixed in 2% paraformaldehyde/culture medium at 37°C for 30 min. Green: PYCR1 protein stained by PYCR1 Polyclonal Antibody (Prod...
MP50786-4: 66510-5-PBS capture and 66510-4-PBS detection (validated in Cytometric bead array) Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. This conjugation ready format makes antibodies ideal ...
The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Pyrroline-5-carboxylate reductase 1 (PYCR1), in particular, by targeting natural antisense polynucleotides of Pyrroline-5-carboxylate reductase 1 (PYCR1). The invention also relates to the ...
CAFs are mesenchymal cells abundant in the stroma of solid tumours and active players in tumour initiation, progression, metastasis and response to anti-cancer therapies1,2. Because of the extensive body of evidence that CAFs support cancer, targeting CAFs has emerged as a unique opportunity to co...
Stefan Mundlos and colleagues report the identification of mutations in PYCR1 that cause autosomal recessive cutis laxa. PYCR1 encodes an enzyme involved in proline metabolism and localizes to mitochondria. Autosomal recessive cutis laxa (ARCL) describes
Consistent with the modes of regulation, RRM1/RRM2 complex controls progression from G1 to S phase, whereas RRM1/RRM2B complex regulates DNA repair8,9,10. Although it is well characterized that RRM2B is involved in the process of DNA repair, mutations of RRM2B have been identified in ...