Among these, the Cre/LoxP system is the most popular in mice, with the two commonly used PV-Cre lines cited over 5600 times. Here we report in the mouse cerebellar cortex that PV-Cre activity is not restricted to inhibitory neurons. Imaging of Cre-activated reporters demonstrated recombination...
Stock 017320, The Jackson Laboratory) or Sst-IRESCre mice (Ssttm2.1(cre)Zjh, JAX Stock 013044, The Jackson Laboratory), to allow Cre-dependent expression of ChR2 in PV (PVChR2) and Sst neurons (Sst-ChR2), respectively. Our study was not designed and sufficiently powered to statistically...
Cdk5 is widely distributed in various tissues, but its kinase activity is restricted in neurons [27,28]. To identify the expression of Cdk5 in neuronal subtypes in the visual cortex, we generated CaMKII, PV, SST or VIP–IRES–Cre; Ai14 mice, which specifically expressed tdTomato in pyramidal...