Idiopathic pulmonary fibrosis (IPF) is characterized by progressive dyspnea, interstitial infiltrates in lung parenchyma and restriction on pulmonary function testing. IPF is the most common and severe of the idiopathic interstitial pneumonias, with most individuals progressing to respiratory failure. Multipl...
Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction. Am J Med Sci. 2011; 341: 435-438.Zoz DF, Lawson WE, Blackwell TS. Idiopathic pulmonary fibrosis: a disorder of epithelial cell dysfunction. Am J Med Sci. 2011; 341 :435–438. doi: 10.1097/MAJ.0b013e31821a9d8e. ...
Pneumoconioses involves the permanent deposition of inorganic material (coal, asbestos, silica, beryllium, etc.) within the pulmonary system. The risk of developingpulmonary fibrosisis related to the duration and intensity of exposure and the size and water solubility of the particles. There is a ...
Pulmonary fibrosis (PF) is a disease of the respiratory system caused by scarring (fibrosis) in the lungs, which makes it harder for patients to breathe. Based on the underlying cause of the scarring, PF can be grouped into several types. Idiopathic pulmonary fibrosis, or IPF, is the ...
(iNOS) as dual therapeutic targets, we analyzed lungfibrosisand the status of the endocannabinoid/CB1R system and iNOS in mice with bleomycin-inducedpulmonary fibrosis(PF) and in lung tissue and bronchoalveolar lavage fluid (BALF) from patients with IPF, as well as controls. In addition, we ...
Background: Idiopathic pulmonary fibrosis (IPF) is a complex disease with a highly variable clinical course and generally poor prognosis. Classified as a rare disease, significant increases in incidence have been recorded worldwide in recent years. Left untreated IPF is extremely debilitating with subs...
Pulmonary fibrosis (PF) is a chronic interstitial lung disorder characterized by abnormal myofibroblast activation, accumulation of extracellular matrix (ECM), and thickening of fibrotic alveolar walls, resulting in deteriorated lung function. PF is initiated by dysregulated wound healing processes triggered...
Pulmonary fibrosis refers to scarring of the lung tissue (fibrosis of the lungs). Learn the causes, symptoms, diagnosis, stages, treatment, life expectancy, and prevention of pulmonary fibrosis.
Cystic Fibrosis Scar tissue can form in the lungs of people afflicted with cystic fibrosis, an autosomal recessive genetic disease that affects proper exocrine gland function, resulting in multiple organ dysfunction, including that of the lungs, pancreas, liver, and intestines. In this disorder, the...
Idiopathic pulmonary fibrosis (IPF) is a non-neoplastic pulmonary disease that is characterized by the formation of scar tissue within the lungs in the absence of any known provocation. IPF is a rare disease which affects approximately 5 million persons