Another non-local application of transdermal microneedles is the delivery of heparin for the treatment of deep vein thrombosis and pulmonary embolism. Heparin is a glycosaminoglycan anticoagulant, with low molecular weight heparin being preferred for clinical use due to a longer shelf life and less ...
No significant ischemic injury (0.0 ± 0.0 mm3) was observed in the sham-operation group. 2.5. Discussion The amino acid glutamate is an excitatory neurotransmitter present in the central nervous system (CNS). After cerebral ischemia-reperfusion injury, the neurotoxicity induced by...
[4] Indications: • tissue adhesion, haemostasis, support of wound healing Contraindications: • arterial or heavy venous bleeding, allergic heparin-in- duced thrombocytopenia, intolerance to bovine products Figure 2: Fibrin glue with application system (Tissucol®) Mechanism of adhesion The ...
Other approaches of designing activatable PDT beacons involve incorporation of multiple PSs to a polymeric carrier like chitosan, dextran, heparin, hyaluronic acid, glycol, polylysine, pullulan etc. Incorporation of PS in polymeric carriers results in efficient self-quenching of fluorescence...
After induction of anesthesia and before systemic heparin- ization, blood was drawn by gravity through the proximal port of the sheath of a Swan-Ganz catheter (Baxter Healthcare Co., Irvine, CA, USA) placed into the internal jugular vein and was collected into a sterile bag...
Furthermore, variations in the sequence lenght and side chains, peptide backbone modification, C-terminal amida- tion, N-terminal acetylation, addition of stabilizing (sugars, salts, heparine) and chelating agents, e.g., ethylenediaminetetraacetic acid (EDTA), conjugations ...