HEPARIN is an extremely potent inhibitor of blood coagulation, and it is on the basis of this property that it has been widely accepted in the clinical treatment of thrombosis1. It is a sulphur-containing mucopolysaccharide which is naturally present in a number of animal tissues, the highest c...
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Skin necrosis occurred locally and distant from the injection site. Heparin-induced antibodies were frequently observed (positive 9/11 articles, negative 2/11). However, severe thrombocytopenia (platelet count <100,000 cells/ml) occurred in only four cases, while platelet count remained normal in ...
a BRT105-103-101 series gel column (8 × 300 mm), a flow-rate of 0.8 mL/min, a column temperature of 40 °C, an injection volume of 25 μL, a refractive index
Article PubMed Google Scholar Paisley MK, Stamper M, Brown J, Brown N, Ganong LH. The use of heparin and normal saline flushes in neonatal intravenous catheters. Pediatr Nurs. 1997;23(5):521–7. PubMed CAS Google Scholar Nelson TJ, Graves SM. 0.9% sodium chloride injection with and...
Suppression of HBP expression by heparin injection following development of AKI in septic mice resulted in a reduction in renal injury severity accompanied by a significantly decreased macrophage infiltration and activation [12]. A meta-analysis including trials investigating heparin administration in ...
Any side effects of the medications, urticaria, bleeding, pain, irritation or hematoma at the injection site, ecchymosis, were also recorded. All women routinely received vitamins including folic acid and iron compounds in the both groups. All demographic and therapeutic outcome ...
LMWH administration is via subcutaneous injection; this has long-term implications on the choice of anticoagulant for prophylaxis, for example, in orthopedic patients recovering from joint replacement surgery or in the treatment of DVT/PE. Patients often dislike injections, especially self-administered on...
6d). TUNEL (terminal deoxynucleotidyl transferase dUTP nick end labeling) staining of the muscle at the injection site also did not reveal any difference to the control, indicating that heparin can be delivered without significant toxicity (Fig. 6e and Supplementary Fig. 22). Discussion Continuous ...
Four hours after the first PBS/heparinoid injection, mice were injected with 2 × 105 LMD MDA-MB 231 breast carcinoma cells into the tail vein. Lungs were collected on day 28 and fixed for histopathology. Twenty sections were cut from each mouse lung at intervals of 50 μm in depth. ...