CDT 正是利用芬顿(或类芬顿)反应,将活性较低的 H2O2转化为有毒的 •OH 来诱导细胞内的氧化应激杀死癌细胞的治疗策略,因其具有很高的选择性,在肿瘤治疗中具有很好的应用前景。然而,受到肿瘤内内源性的 H2O2浓度(～50-100 μM)的限制,CDT 的抗癌效果往往...
基于此,在粗糙表面的碳壳/Fe3O4杂化纳米颗粒(RCF)的基础上设计了一种高效抗菌体系,通过增强材料与细菌的粘附、提高NIR-II光响应的PTT/CDT协同抗菌效果。RCF可催化低浓度的过氧化氢产生自由基,同时在低功率密度(0.5W/cm2)NIR-II激光照射下RCF具有PTT/CDT协同广谱抗菌能力。此外,RCF在大鼠的伤口感染模型中显示出...
Chemodynamic therapy (CDT), which uses metal ions to covert endogenous hydrogen peroxide into highly reactive hydroxyl radicals, is an newly-developing strategy for cancer therapy. However, poor drug delivery efficiency and restricted catalytic performance hinder the therapeutic potential of CDT. Herein,...
本文用傅立叶红外光谱(FT-墩)、差热分析(DSC)、临界溶解时间(CDT)等分 析方法研究了热定型和染色对PTT纤维结构的影响,探讨了热定型对P1T纤维可染 性的影响,同时进行了多项PTT纤维的基本染色性能试验,探讨了不同染色温度对 上染百分率及表观色深值的影响、不同染料的升温上染特性、不同染料的移染性能和 ...
cdt 'n .C0 111.c n 60 oC ×20 min,脱水 ,烘干 。若织造中 没有 沾污 ,可不 加去油污剂 ,直接进行柔软整理。 ( 2) 拉 、剪 、磨毛 可根据产品的设计要求进行。 (3) 定形 大圆机生产的 P1TI’弹性纤维产品,一般不 需要染色前的预定形,染色后的定形温度为 130 ～150 oC , ...
"name": "ptt-scr", "version": "1.2.3", "lockfileVersion": 1, "requires": true, "dependencies": { "@babel/cli": { "version": "7.1.5", "resolved": "https://registry.npmjs.org/@babel/cli/-/cli-7.1.5.tgz", "integrity": "sha512-zbO/DtTnaDappBflIU3zYEgATLToRDmW5uN/EGH1...
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Conclusions: This study not only provided a new idea for PTT combined with hypoxia-activated chemotherapy and CDT for drug-resistant tumors but also explored a vital theory for real-time monitoring of hypoxia during treatment.doi:10.1186/s12951-024-02653-8Chang, Peng...
Herein, a nanoplatform containing mesoporous Fe3O4@TiO2 microspheres was developed for near-infrared (NIR)-light-enhanced chemodynamical therapy (CDT) and PDT. Titanium dioxide (TiO2) has been shown to be a very effective PDT agent; however, the hypoxic tumour microenvironment partly affects its ...