Why is the test used? The test is used to try and determine the cause of high or low levels of calcium in the blood; the test can distinguish between problems related to the parathyroid and those not associated with the parathyroid gland. The test may also be used for patients who are ...
PTH-Related Protein [PTHrP]点击次数:196发布时间:2009/11/2更新日期:2012/3/8 16:46:51 所在地:中国大陆 产品型号: 简单介绍:美国UCL和BIOSIS公司 及其他知名公司的酶联免疫吸附方法ELISA试剂 盒和免疫组化IH试剂盒石蜡切片P 冰冻切片F 免疫印迹WB 流式细胞检 测FC方法,以及单克隆抗体,和多克隆抗体相关标签...
is a hormone secreted by parathyroid cells. PTH stimulates bone formation to increase bone mass and strength in rats and humans. Within the PTH molecule, the essential activity is associated with the first 34 amino acids at the amino terminus of the molecule. This hormone elevates blood Ca2+ ...
Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to...
Parathyroid hormone (PTH)1 is a major regulator of ionized calcium and phosphate concentrations in the blood and extracellular fluids, and PTH-related protein (PTHrP) is a vital developmental morphogen (1, 2). These two peptide ligands mediate their actions by binding to the same receptor, the...
while prolonged induction is related to bone destruction34. Here, we have found that cPTH significantly increased the RANKL/OPG ratio (an indicator of bone resorption) in subcortical trabecular bone and bone marrow in both WT and MCP-1−/−mice compared with their vehicle-infused groups. Thes...
Replenishment of PTH1 receptor pool by peripheral receptor gene delivery in spontaneously hypertensive rats (SHR) does not affect blood pressure but increases plasma renin activityplasmareninactivityrenalvesselsparathyroidhormone-relatedprotein(PTHrP)
The ratio of phosphorylated protein to total protein was also calculated (n = 3) (E). Data are shown as the mean ± SD. ∗∗p < 0.01 and ∗∗∗p < 0.001 by one-way ANOVA. IRDS, interferon-related DNA damage resistance signature; JAK, Janus kinase; ND, not detected; ns, ...
The type 1 parathyroid hormone receptor (PTH1R), a G-protein-coupled seven transmembrane receptor (GPCR), is the primary functional receptor for both endogenous PTH and PTH-related protein (PTHrP) ligands. PTH1R plays critical roles in regulation of calcium metabolism, skeletal development, and ho...
SDF-1αbelongs to the C-X-C chemokine family, and exerts multiple biological functions through its receptor CXCR4, a G-protein coupled receptor16,17. SDF-1α/CXCR4 axis is important for embry- onic organ development and essential for physiological functions, including blood homeostasis,...