PTH binding to PTH1R preferentially simulates endosome- mediated long cAMP signaling, whereas PTHrP prefers to stimulate canonical short cAMP signaling.9 The stabilized PTH analog D6 exhibits a longer half-life than native PTH(1–34) in the blood stream, inducing an increase in the blood Ca2+...
Calcium deficiency, not sodium excess, is an overlooked link in hypertension (high blood pressure) likely due to overstimulation of parathyroid hormone (PTH). 由于甲状旁腺激素(PTH)的过度刺激,钙缺乏,而不是钠过量,是高血压中被忽视的一个环节。 Hypertension 1980 Mar-Apr;2(2):162-8.Enhanced par...
One patient required blood transfusion for post-polypectomy bleeding. There were no other complications. Five patients died of unrelated causes during a median follow-up of 49months (range 1–120). Twenty patients (28.9%) underwent colonic imaging. Colorectal polyps were found in 40% (8/20) ...