PTH binding to PTH1R preferentially simulates endosome- mediated long cAMP signaling, whereas PTHrP prefers to stimulate canonical short cAMP signaling.9 The stabilized PTH analog D6 exhibits a longer half-life than native PTH(1–34) in the blood stream, inducing an increase in the blood Ca2+...
Again blood samples were taken at two points in time, i.e. 48 hours after administration and after 8 weeks. Concerning the time course of 25(OH)D3 again no significant changes could be demonstrated. Our study is the first study to examen the time course of 25(OH)D3 during human ...