We evaluated doxercalciferol (1伪-hydroxyvitamin D2) as an alternative therapy in a randomized, double-blinded, placebo-controlled, multicenter trial. Methods: Fifty-five adults with stage 3 or 4 CKD and an intact PTH (iPTH) level greater than 85 pg/mL (ng/L) completed 8 baseline weeks, ...
It has been proposed that 7-84 PTH fragment may play a role in skeletal resistance to PTH observed in stage 5 CKD.17 Indeed, the assay used for measuring iPTH in this study, that is Immulite, presents—according to the study conducted by Souberbielle et al.9—a ratio of recovery of ...
Abstract. Introduction: A very low parathyroid hormone (PTH) level (VLPL) is associated with an increased risk of adynamic bone disease, vascular
Purpose: Cardiovascular diseases are a common cause of mortality in patients with end stage renal disease and are associated with vascular calcification (VC) and arterial stiffness. In addition to high turnover bone disease, there is substantial evidence that low levels of serum intact PTH (iPTH)...
in intraoperative use The measured PTH (1‑84) value of a patient’s sample can vary depending on the testing procedure used. The laboratory finding must therefore The determination of PTH intraoperatively during adenoma resection in the always contain a statement on the PTH (1‑84) assay ...
Recently, acetate-free citrate containing dialysate (A(−)D) was developed. We have already reported about the significant effect of A(−)D on metabolic acidosis, anemia, and malnutrition in maintenance hemodialysis (MHD) patients. In this study, we
CKD-MBD II MP 516 KDIGO-RECOMMENDED PTH LEVEL ACCELERATES AORTIC CALCIFICATION IN PATIENTS NEW TO HEMODIALYSIS Introduction and Aims: Vascular calcification is an important factor influencing cardiovascular complications and the vital prognosis in hemodialysis patie......
Elevated serum level of fibroblast growth factor-23 (FGF23) is associated with adverse outcomes in dialyzed patients. The CUPID study compared the efficacy of a cinacalcet-based regimen with conventional care (vitamin D and P binders) for achieving the s
Kovesdy et al compared the effect of paricalcitol and ergocal-ciferol on parathyroid hormone (PTH) levels in 80 patients with chronic kidney disease (CKD) stage 3 or 4 and found that PTH levels decreased only in patients receiving paricalcitol. However, mean 25-hydroxy vitamin D level ...
KDOQI PTH target associated with high risk of low-turnover bone disease in stage 5 CKDBarreto FC et al . ( 2008 ) K/DOQI-recommended intact PTH levels do not prevent low-turnover bone disease in hemodialysis patients . Kidney Int 73 : 771 – 777 KDOQI guidelines recommend maintenance of ...