P. aeruginosa is resistant to high concentrations of salts and dyes, weak antiseptics, and many commonly used antibiotics. These properties of P. aeruginosa are critical factors for its ecological success, which also help explain the ubiquitous nature of the organism and its prominence as a ...
Pseudomonas aeruginosa infections are difficult to treat due to rapid development of antibiotic drug resistance. The synergistic combination of already-in-use drugs is an alternative to developing new antibiotics to combat antibiotic-resistant bacteria. Here we demonstrate that bismuth-based drugs (bismuth...
Pseudomonas aeruginosa has become an important cause of gram-negative infection, especially in patients with compromised host defense mechanisms. It is the most common pathogen isolated from patients who have been hospitalized longer than 1 week, and it is a frequent cause of nosocomial infections. ...
aeruginosa sensitive to ciprofloxacin. The patient then began to receive ciprofloxacin 500 mg po bid. Within 3 days the diarrhea stopped. Oral ciprofloxacin therapy was continued for 10 days and the patient remained free of symptoms with formed stools thereafter. DISCUSSION: Diarrhea following the ...
Antibiotic efficacy can be antagonized by bioactive metabolites and other drugs present at infection sites. Pseudomonas aeruginosa, a common cause of biofilm-based infections, releases metabolites called phenazines that accept electrons to support cellul
OBJECTIVE To explore the antibiotic activity and changing trend of clinically isolated Pseudomonas aerginosa strains.METHODS The Drug-resistance of 485 clinically isolated to 18 kinds of common antibiotics P.aeruginosa strains was performed by Kirby-Bauer method.The drug sensitiveity test was indged bas...
aeruginosa adapts to and persists within the CF airway. Yet knowledge gaps remain, and prevention and treatment strategies are limited by the lack of sensitive detection methods and by a narrow armoury of antibiotics. Further developments in this field are urgently needed in order to improve ...
Antimicrobial resistance is a global public health emergency, and for the last century, the medical world has been struggling with multiple resistance or even lack of sensitivity to antibiotics to the latest generation. Pseudomonas aeruginosa is a microorganism that shows a h...
Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant pathogen Pseudomonas syringae. The bacteriophages that infect Pseudomonas spp. mirror the widespread and diverse nature of their ho...
We characterize the activity of fluorofolin, a potent inhibitor of dihydrofolate reductase, against Pseudomonas aeruginosa. By exploiting a divergence in thymidine metabolism, fluorofolin becomes selective for P. aeruginosa in the presence of thymine, de