aeruginosa) and their antibiotic resistance genes (ARGs) in aquatic settings and the alternative treatment ways. P. aeruginosa in a various aquatic environment have been identified as contaminants with impacts on human health and the environment. P. aeruginosa resistance to multiple antibiotics, such ...
Currently, a select few antibiotics are somewhat effective, including fluoroquinolones, imipenem and gentamicin. Virtually all cystic fibrosis patients will develop an MDR strain. Diagnosis of P. aeruginosa infection relies on isolation and laboratory identification of the bacterium [162]. P. aeruginosa ...
aeruginosa against Trimetoprime Solfametoxasole and Ciprofloxacin (55.33%), Amikacin (61%), Imipenem (33%), which were identified as the most effective antibiotics in this study. In conclusion, indeed most Pseudomonas aeruginosa strains infections are treated as soon as possible due to their ...
Nevertheless, much remains to be uncovered about interactions betweenP. aeruginosaand host immune responses, including mechanisms of drug resistance by known or unannotated bacterial virulence factors as well as mammalian cell signaling pathways. The widespread use of antibiotics and the slow development o...
Pseudomonas aeruginosa is a leading cause of hospital-acquired infections for which the development of antibiotics is urgently needed. Unlike most enteric bacteria, P. aeruginosa lacks enzymes required to scavenge exogenous thymine. An appealing strategy
Antibiotics for Pseudomonas aeruginosa sepis: inadequate proof of efficacy.Authors Davis, S D Iannetta, A Wedgwood, R J Type Published Article Journal The Journal of Infectious Diseases Publisher Oxford University Press (OUP) Publication Date Jul 01, 1971 Volume 124 Issue 1 Pages 104–...
The biosynthesis of membrane proteins of Pseudomonas aeruginosa was examined using various antibiotics (puromycin, streptomycin, chloramphenicol, tetracycline, and rifampin). Among six major membrane proteins separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, the biosynthesis of two membrane...
Pipercaillin and carbenicillin are still highly effective against P. aeruginosa, while the antipsychotic drug Tz is a potent agent able to eliminate drug resistance plasmids, which are much larger in size than the plasmids of other Gram negative bacteria. Since many antibiotics are administered ...
(Driscoll et al., 2007).P. aeruginosainfections are always difficult to treat due to the natural resistance of this bacterium (Obritsch et al., 2005). Consequently, a therapy with two or three antimicrobial agents is typically used (Lodise et al., 2007; Szaff et al., 1983; Valerius ...
Pseudomonas aeruginosa infections are difficult to treat due to rapid development of antibiotic drug resistance. The synergistic combination of already-in-use drugs is an alternative to developing new antibiotics to combat antibiotic-resistant bacteria. Here we demonstrate that bismuth-based drugs (bismuth...