First, because a recent study has defined tPSA thresholds for identifying or excluding advanced PCa, as an aid to personalize management of the diagnostic workup, by using well calibrated risk prediction models and tPSA results exclusively obtained by Roche assay [13]. Noteworthy, most of ...
Assessment of DRE and PSA as Diagnostic and Screening Tool for Carcinoma of the Prostate in Rural NigeriaE IrekpitaC OwobuE AigbeG ObasikeneA IgbeAssociation of Surgeons of East Africa / College of Surgeons of East Africa (COSECSA)
Objective To evaluate the effect of a single prostate-specific antigen (PSA) screening intervention and standardized diagnostic pathway on prostate cancer–specific mortality. Design, Setting, and Participants The Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) included 419 582 men ...
Percentage of fPSA contributes to modest diagnostic enhancements above and beyond tPSA alone among men in the “diagnostic gray zone”54. High %fPSA was also shown to be associated with worse survival outcome in patients with biochemical recurrence, indicating that fPSA may have role in progression...
"But at the same time, the study did not delve into any detail as to why the tests were ordered, and anyone in a urologist's office may have more advanced reasons to be there ― they may be symptomatic, and these are the patients who actually need the PSA as a diagnostic test for...
As such, the reliability of of the serum PSA level as a sole screening and diagnostic tool for prostate cancer is controversial. Recently, it has been shown that fasting extremes can affect concentrations of serum chemistryanalytes, thus raising the question of whether or not fasting has an ...
【关键词】 前列腺癌;磁共振成像;前列腺特异性抗原;早期前列腺癌抗原 2 【中图分类号】 R698 【文献标识码】 A DiagnosticvalueofMRIcombinedwithserum TPSA,FPSA/TPSA andEPCA 2inprostatecancer SU Jingjing,LU Wenquan,SHAO Baoer,LELingyun△ .DepartmentofOncology,YuyaoPeople′sHospital,Yuyao 315400,Zhejiang...
Third, no previous studies have systemically evaluated the diagnostic value of measuring GSTP1 promoter methylation in different types of body fluids for prostate cancer diagnosis. This study indicates that the use of plasma/serum or urine samples for prostate cancer diagnosis is an important, non-...
Screening for prostate cancer continues to generate controversy because of concerns about over-diagnosis and unnecessary treatment. We describe the rationale, design and recruitment of the Cluster randomised triAl of PSA testing for Prostate cancer (CAP)
Conclusions Our results confirm that the ratio C/T improve the diagnostic capacity of the total PSA between 4-10 ng/ml. Moreover, the rectal examination does not influence the selection of ratio C/T cut-off suggestives of CaP neither the diagnostic efficacyAccess...