death from prostate cancer, and death from any cause, compared with lower PSA velocity. For example, 24 of 262 men with annual PSA velocity of more than 2.0 ng/mL, but only 3 of 833 patients with lower PSA velocity, died from prostate cancer. In multivariable analysis, PSA velocity...
Cancer vaccines may improve outcomes by inducing an immune response to tumor antigens. This randomized, phase II clinical trial was designed to determine if a PSA-based vaccine could induce a specific immune response when combined with radiotherapy in patients with localized prostate cancer. The ...
and the PSA test was originally approved by the FDA in 1986 to monitor the progression of prostate cancer in men who had already been diagnosed with the disease. In 1994, FDA approved the PSA test to be used in c...
[4]MA C G, YE D W, LI C L, et al. [Epidemiology of prostate cancer from three centers and analysis of the first-line hormonal therapy for the advanced disease] [J]. Zhonghua Wai Ke Za Zhi, 2008, 46(12): 921-5. [...
[5] Russo GI, et al. A SystematicReview and Meta-analysis of the Diagnostic Accuracy of Prostate Health Indexand 4-Kallikrein Panel Score in Predicting Overall and High-grade ProstateCancer.Clinical Genitourinary Cancer(2016). doi: 10.1016/j.clgc.2016.12.022 ...
aThe data on PSA testing to detect prostate cancer has long been shaky — so much so that the discoverer of PSA (or prostate-specific antigen, an enzyme made by the prostate) himself decried the test two years ago as “hardly more effective than a coin toss.” 关于PSA的数据测试查出摄护...
In the current analysis, the researchers looked at the performance of PSA as a marker for prostate cancer, particularly foraggressive cancer. Among men taking dutasteride, the investigators found that any subsequent rise in PSA levels over the course of the study was more likely to be linked to...
近年来,PSA同源异构体2(p2PSA) 及其衍生物前列腺健康指数(prostate health index,PHI)逐 渐受到关注。研究结果表明,p2PSA与高分级前列腺癌相关, 特别是对于总PSA为4～10ng/ml的人群而言,PHI诊断前列 腺癌的效力优于总PSA,可以减少不必要的前列腺穿刺活检。 通过总PSA、游离PSA和p2PSA计算PHI,公式如下: PHI = ...
The serum determination of the fPSA/tPSA ratio is an excellent index of PCa for subjects younger than 60 years of age; the clinical utility of PSA mRNA identification in circulating cells needs to be validated by large follow-up studies, and the analysis of PSM mRNA seems to be of no ...
[5] Russo GI, et al. A SystematicReview and Meta-analysis of the Diagnostic Accuracy of Prostate Health Indexand 4-Kallikrein Panel Score in Predicting Overall and High-grade ProstateCancer.Clinical Genitourinary Cancer(...