Kjellberg RN, Abe M: Stereotactic bragg peak proton beam therapy, in Lunsford LD (ed): Modern Stereotactic Nearosurgery. Boston: Martinus Nijhoff, 1988, pp 463-470Kjellberg RN, Abe M: Stereotactic Bragg peak proton beam therapy, in Lunsford LD (ed): Modern Stereotac- tic Neurosurgery. ...
proton beam therapy (PBT) effectively allows the delivery of high-radiation doses to tumor cells and very low or zero doses to the normal cells, which is recognized as an ideal
A technique is described that permits precise localization of brain targets and their irradiation using the end of the range of a proton beam, the Bragg peak, where ionization effects may be several times greater than elsewhere along the beam path. A stereotactic instrument was devised to guide ...
Proton beam therapy is an excellent option for periocular tumors. Its sharp lateral penumbra allows for the sparing of normal tissues, such as the cornea, whereas the zero-exist dose of the proton’s Bragg peak allows for the sparing of normal tissues such as the optic nerve and retina beyon...
With this proton beam it is possible to investigate the interaction of high LET protons with EBT3 films with narrow energy spreads, as compared with therapeutic proton beams in the Bragg peak region. The data of the beam energy at the position of the film were used to simulate the energy ...
Proton beam therapy has a slightly higher biological effectiveness (approximately 1.1 times) than photon therapy and reduces the adverse effects on the normal liver because of the nature of the Bragg peak [11, 12]. The liver is a movable organ due to respiratory motion. Therefore, specific tech...
Proton beam therapy (PBT) makes it possible to deliver a high concentration of radiation to a tumor using its Bragg peak, and it is simple to utilize as its radiobiological characteristics are identical to those of photon beams. PBT has now been used for half a century, and more than 60...
The Bragg peak of the proton beam has been used to treat 571 patients with pituitary related disease. The method is associated with no mortality, low morbidity, short hospital stay and low cost. Of the pituitary tumors, 254 procedures were done for acromegaly, 56 for Cushing's disease, and...
detector for the microdosimetric characterization of clinical 62MeV ocular therapy proton beams.#A novel diamond microdosimeter with a well-defined sensitive volume was fabricated and tested with a monoenergetic and spread-out Bragg peak (SOBP) of the CATANA therapeutic proton beam in Catania, Italy...
Proton irradiation exhibits an entrance portion of the beam (ENT) where dose is deposited sparsely and a Bragg Peak (BP) with virtually no 'exit dose' thereafter. ATMi renders cells uniquely hypersensitive to proton BP, and BP+ATMi may increase the response of Mismatch Repair proficient (pMMR)...