In patients with dipstick proteinuria, quantification (grams per day or grams per gram creatinine) was performed in only 34% and ranged from 0.16 grams to 8.0 grams. Patients with larger amounts of proteinuria had more severe acute renal failure, were more likely to receive a renal biopsy, ...
The lowest ratio was 3.4 and the highest 30.2 mg/mg – these figures approximately equate to albumin excretion expressed as grams per day per 70 kg body weight. The tubules have a high capacity but low affinity for albumin [15], which implies that conclusions on glomerular permselectivity can...
decrease in 24hUP with a sensitivity of 94%. In conclusion, the uACR is a reliable and convenient method for ruling out proteinuria >500 mg per day, prognosticating renal outcomes, and assessing renal response to therapy. Further studies are needed to validate the uACR cutoffs proposed in ...
Total protein excretion was expressed as grams per surface area per day and the urinary protein/creatinine ratio as milligrams of protein per milligram of creatinine. Degrees of proteinuria were designated as physiologic (<0.01 gm/m 2/day), intermediate (>0.1 and <1.0 gm/m 2/day), or ...
All patients started dapagliflozin 10 mg once per day after baseline data were registered. The total follow-up was 12 months. The main outcome was the decline in eGFR and the reduction in 24-hour proteinuria from SGLT2i initiation to 1,3, 6, 9, 12 months, end-stage renal disease, or ...
METHOD. 63 adult patients with biopsy-proven IgA nephropathy, eGFR 鈮 30 mL/min/1.73 m2 (CKD-epi), and total urine protein of >0.5 grams/day at screening were included. Patients with secondary IgAN were excluded. All receiving maximally tolerated RASi for at least 12 weeks. All patients ...