The DZBB fold is not found in any modern protein, although its structure shares similarities with RIFT and OB. Indeed, DZBB could be transformed into them through simple engineering experiments. Furthermore, the
Similarities and differences in the nucleic acid chaperone activity of HIV-2 and HIV-1 nucleocapsid proteins in vitro. Retrovirology. 2014;11:54. doi:10.1186/1742-4690-11-54.Pachulska-Wieczorek K, Stefaniak AK, Purzycka KJ. Sim- ilarities and differences in the nucleic acid chaperone ...
Indeed, numerous ACBD-like sequences with significant similarities could be retrieved (see Fig. S3 for sequence comparison) and were used for a phylogenetic reconstruction. As no extended forms were found among prokaryotes, the small forms from eukaryotes were routed with the prokaryotic sequences ...
Pathogenesis-related 10 (PR-10) is a group of small intracellular proteins that is one of 17 subclasses of pathogenesis-related proteins in plants. The PR-10 proteins have been studied extensively and are well-recognized for their contribution to host de
In this paper we present sufficient protein and nucleic acid sequence data to establish the identification of all the protein components in the 50 S subunit of a land plant chloroplast ribosome. Similar results for chloroplast 30 S subunit are in the accompanying article (83). Taken together thes...
To understand the evolutionary history of this gene family, an attempt was made to identify correlations between chromosomal locations of FREP and FBG domain sequence similarities among the family members. The genes for the FREP family in A. gambiae have been mapped to specific A. gambiae chromoso...
Using protein structure to predict function, interactions, and evolutionary history is still an open challenge, with existing approaches relying extensively on protein homology and families. Here, we present Machaon, a data-driven method combining orient
The mammalian system: similarities and differences between Get4/5/Sgt2 and BAG6/SGTA Mammalian cells express a complex consisting of GET4 (Get4 homolog), UBL4A (Get5 homolog), and BAG6 (no yeast homolog identified), which is termed the BAG6 complex1,11,14. In contrast to Get5, UBL...
Structure comparison and alignment are of fundamental importance in structural biology studies. We developed the first universal platform, US-align, to uniformly align monomer and complex structures of different macromolecules—proteins, RNAs and DNAs. T
Also provided are fragments of the subject nucleic acids and the peptides encoded thereby, as well as antibodies to the subject proteins and transgenic cells and organisms. The subject protein and nucleic acid compositions find use in a variety of different applications. Finally, kits for use in...