Finally, we designed experimental verification methods of human DEPDC expression at the mRNA level in hepatocellular carcinoma (HCC) and adjacent normal tissues. The phylogenetic analysis showed that the DEPDCs superfamily can be divided into three clusters. Moreover, the 188D and 20D features can ...
The aging process is regarded as the progressive loss of physiological integrity, leading to impaired biological functions and the increased vulnerability to death. Among various biological functions, stress response capacity enables cells to alter gene expression patterns and survive when facing internal ...
but the expression patterns of the genes encoding these enzymes in a multicellular organism have not yet been systematically examined. Genes encoding glycolytic and TCA cycle enzymes are a particularly attractive target for a systematic analysis of expression patterns because their products form pathways....
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Differences between the recombinant xylose-utilizing Saccharomyces cerevisiae strain TMB 3399 and the mutant strain TMB 3400, derived from TMB 3399 and displaying improved ability to utilize xylose, were investigated by using genome-wide expression analysis, physiological characterization, and biochemical assa...
RNA-Seq Data Processing and Gene Expression Analysis Strand-specific RNA-seq reads from control siRNA treatment, and each hnRNP depletion experiment were processed as previously described (Polymenidou et al., 2011). An average of 70% of reads mapped uniquely to our gene structure database, using...
(A) Foreground sets in TSMA are defined by differential gene expression analysis of RNA-seq or microarray datasets, usually by selecting statistically significantly upregulated and downregulated genes. The background set is all of the genes in the microarray platform or all of the measured genes in...
combination of fungal cell permeabilization, cell-penetrating ability and nucleic acid-binding activity of AFP determines its potent antifungal activity againstM. grisea.These results are discussed in relation to the potential of the AFP protein to enhance crop protection against fungal diseases....
The proteins of the sarcoplasmic reticulum and the sarcolemmal Na+/Ca2+ exchanger are the most important tools for Ca2+ homeostasis in the cardiomyocyte, and their molecular cloning has allowed prediction of structure/function analysis. The investigation of function and gene expression of these protei...
Regulation of gene expression at the post-transcriptional level is mainly achieved by proteins containing well-defined sequence motifs involved in RNA binding. The most widely spread motifs are the RNA recognition motif (RRM) and the K homology (KH) domain. In this article, we survey the complet...