We also explored the prevalence and functional impact of multinucleotide polymorphisms (MNPs), in cases where multiple substitutions were observed within the same codon in at least one individual. We found 5,945 MNPs (mean = 23 per sample) in ExAC (Extended Data Fig. 2a), in which anal...
Nucleotide composition in protein-coding and non-coding DNA in the zygomycete Phycomyces blakesleeanus - Corrochano, Ruiz-Albert - 2004 () Citation Context ...otide at the silent third codon position may change more freely than those on the other codon positions due to lower selective ...
nucleotide sequence coding at least one protein for lysing the microorganism in the cytosol of mammalian cells and for intracellularly releasing plasmids or expression vectors, which are contained in the lysed microorganism; and a fourth component which is at least one nucleotide sequence for at least...
A protein-coding gene is composed of a series of nucleotide triplets – the codons – that encrypt not only the protein content but also the start and stop signals. There are 64 (43) codons in the canonical genetic code, which encode 20 amino acids with redundancy. Hence, there are synony...
(Supplementary Data6). Celiac disease was identified to have the most single nucleotide polymorphisms (SNPs,N = 30), followed by psoriasis (N = 16) and asthma (N = 13). The mean values for disease-predisposing and disease-protective alleles were 1.47 and 0.70, respectively. ...
It is shown that in both bacteria, regardless of nucleotide content, u0394rS u2014 the relative difference of the two entropies u2014 is significantly greater in protein-coding regions, when compared with noncoding RNA segments. 展开 关键词: DNA Sequence Shannon Entropy. DOI: 10.1142/S...
https://doi.org/10.1016/j.bbagrm.2019.194434Get rights and content Under a Creative Commons license open accessHighlights Abstract The 43-kDa transactive response DNA-binding protein (TDP-43) is an example of an RNA-binding protein that regulates RNA metabolism at multiple levels from transcription...
We found nucleotide substitutions specific to B chromosomes in two cases. The B chromosomal second exon of LRRIQ3 gene carries a transition (G > A) (valine141 to isoleucine141); the comparison was based on both the roe deer without B chromosomes and cattle, in the DOP-library of B ...
Nucleotide sequences coding protein for use in the treatment of cellular proliferation, differentiation, cardiovascular, liver, pain, metabolic, brain, blood disorders, hematopoietic and platelet disordersdoi:US20020127568 A1The invention provides isolated nucleic acids molecules, designated 47324 nucleic acid...
2. NGS platform is particularly essential in the advancement of modern genomic studies that mainly focus on determining genome sequences and deciphering the significant genome features of millions of nucleotide sequences. Genome sequence determination is now the simplest part of genome researches. ...