354 proteins with sex-biased expression identified in the current work (Supplementary Table16). Moreover, we found that 25% of the causal genes in brain traits, on average, had sex-biased protein expression (range 5–50%; Fig.3a). Further...
This repository is inspired by the remarkable work of Kevin Kaichuang Yang and their outstanding project Machine-learning-for-proteins. We have established this repository to provide a specialized and focused platform for the field of Deep Learning for Protein Design, a rapidly advancing domain in co...
ZHANG Yong Hong is the guarantor of this work and, as such, had full access to the data and takes responsibility for the accuracy of data analysis. CONFLICT OF INTEREST There are no conflicts of interest to declare.References [1] Strong K, Mathers C, Bonita R. Preventing stroke: saving...
A recent study introduces a series of approaches that predict protein fitness and stability after the introduction of mutations. The work focuses on combining different data and pre-training to overcome data scarcity. Minghui Li News & Views08 Nov 2024Nature Computational Science ...
3.1 The role of vacuolar protein sorting 27 in MVB sorting The class E Vps protein Vps27p belongs to the ESCRT-0 complex and plays an important role in MVB sorting. In the process by which ubiquitinated cargo proteins are recruited and clustered, Vps27p may work upstream of the ESCRT-...
Of course, if your doctor suggests that your baby or toddler needs some catch-up growth or requires more protein due to a medical condition, work with your medical team to put together a customized plan to ensure your toddler getsthe nutrition they needfor their own unique development. ...
Green factors positively influence rates of protein synthesis while red factors work to inhibit protein synthesis. For simplicity of illustration, the ribosome is shown independent of the endoplasmic reticulum (factors not drawn to scale). Changes in mTORC1 activity can have widespread influence, ...
Many people drink protein shakes right after a workout to help repair their muscles and help them grow. Here are some other possible benefits of protein shakes: May help with weight loss. Because protein takes a while to digest, it can help you feel full longer. ...
(MS) has become a prominent technique in the field of structural biology due to its ability to provide structural information for proteins and protein complexes. MS can be particularly beneficial because it is faster, can work for heterogeneous samples, can be used routinely at all stages of a...
skeletal muscles reveal that deleting two super-repeats from the A-band segment of titin reduces thick filament length with each of titin’s C-zone repeats being responsible for a quantal 43 nm thick filament length. Below we discuss the structural and functional findings of this work in ...