Objective To investigate whether increasing protein intake to 1.3 g/kg/d in older adults with physical function limitations and usual protein intake within the RDA improves lean body mass (LBM), muscle performance, physical function, fatigue, and well-being and augments LBM response to a muscle ...
early childhood, puberty and adulthood)9and in splicing10. Reasons for sex-biased gene expression for some autosomal genes may be related to the presence of androgen or estrogen hormone response elements11. Sex-biased gene expression likely contributes to differences ...
(74).Protein-protein interactionanalysis is pursued to characterize signaling networks, discover the components ofprotein complexes, and identify the contexts in which a protein may function in health and disease(75). A powerful approach to analyze protein-protein interaction is affinity purification-MS...
Predicting the structure of interacting protein chains is a fundamental step towards understanding protein function. Unfortunately, no computational method can produce accurate structures of protein complexes. AlphaFold2, has shown unprecedented levels of accuracy in modelling single chain protein structures. ...
We tested the hypothesis that concentrations of non-protein-bound (free) and loosely bound (bioavailable) sex hormones are associated with cognitive function in older women. We measured cognitive performance with a modified mini mental status examination (mMMSE) at baseline (1986–88) and 6 years...
A proteinmoleculeis very large compared with molecules ofsugarorsaltand consists of manyamino acidsjoined together to form long chains, much as beads are arranged on a string. There are about 20 different amino acids that occur naturally in proteins. Proteins of similar function have similar amino...
3. Function to Scaffold These models design backbone/scaffold/template in Cartesian coordinates, contact maps, distance maps and φ & ψ angles. Including conditional/unconditional generative models. 3.1 GAN-based Generative modeling for protein structures Anand, Namrata, and Possu Huang NeurIPS 2018 Fu...
We postulated that there may be sex differences in the relationship between CRP and body fat. Methods: We measured CRP and body fat parameters in 1166 men and 1413 women ages 30-65 in the population-based Dallas Heart Study. Total fat mass (TFM) was measured using dua...关键词:...
Posttranslational modifications (PTMs) of proteins, the major mechanism of protein function regulation, play important roles in regulating a variety of cellular physiological and pathological processes. Although the classical PTMs, such as phosphorylation, acetylation, ubiquitination and methylation, have be...
The effect of prolactin on reproductive function in female Japanese quail (Coturnix coturnix japonica). The anti-gonadal or anti-gonadotropic actions of prolactin in Japanese quail (Coturnix coturnix japonica) were re-investigated. Treatment of mature regularly laying quail with 16 I.U. of ovine pro...