Protein synthesis refers to the biological process whereby amino acids are assembled by peptide bonding into specific polypeptide sequences in accord with genetic blueprints encoded by deoxyribonucleic acid (DNA). From: Encyclopedia of Stress (Second Edition), 2007 About this pageAdd to MendeleySet ale...
第六章 蛋白质合成(Protein synthesis).ppt,Chapter 6 Figure 6.1 Ribosomes are large ribonucleoprotein particles that contain more RNA than protein and dissociate into large and small subunits. Figure 6.2 Electron microscopic images of bacterial ribosomes
catalyzed reactions relying on the recognition and binding between helicase and DNA double helix (responsible for DNA unzipping), DNA polymerase and single strand DNA (responsible for base insertion and DNA synthesis), and ligase and discontinuous DNA segments (responsible for stitching these segments)...
Thus, we will discuss some examples of genetically fused enzymes and their application in carbon‑carbon bond formation and oxidative reactions, generation of chiral amines, synthesis of carbohydrates, biodegradation of plant biomass and plastics, and in the preparation of other high-value products. ...
While significant advances have been made in predicting static protein structures, the inherent dynamics of proteins, modulated by ligands, are crucial for understanding protein function and facilitating drug discovery. Traditional docking methods, frequ
c The chemical structures of inhibitors of MDM2/p53 Full size image The X-ray crystallography disclosed the details of the MDM2/p53 interaction. The interaction between MDM2 and p53 involves four key hydrophobic residues (Phe19, Leu22, Trp23, Leu26) in an α-helix formed by p53 and a ...
DNA encoding a basic fibroblast growth factor An isolated DNA sequence encoding an angiogenic factor protein consisting of a single-polypeptide-chain protein having at least one active site possessing mitotic and chemotactic activity and the ability to stimulate protease synthesis, ... DA Moscatelli,DB...
The lamins are the major architectural proteins of the animal cell nucleus. Lamins line the inside of the nuclear membrane, where they provide a platform for the binding of proteins and chromatin and confer mechanical stability. They have been implicated
DNA and protein synthesisDNA in the cell nucleus carries a genetic code, which consists of sequences of adenine (A), thymine (T), guanine (G), and cytosine (C) (Figure 1). RNA, which contains uracil (U) instead of thymine, carries the code to protein-making sites in the cell. To...
of proteins over long timescales7. For example, translation of a synonymous variant of thefrqgene in the fungusNeurosporaresulted in the synthesis of FRQ protein with altered conformations that bound 50% less to a partner protein, resulting in a significantly altered circadian rhythm that persisted ...