For clinical and pharmacological purposes, the barrier between the intravascular compartment and any secondary body fluid compartment can be characterized by concentration ratios of selected endogenous marker proteins, obtained under steady state equilibrium conditions. The hydrodynamic radii of these ...
Rifamycin can inhibit RNA synthesis in human mitochondria, but at much higher doses than those used for bacterial infections. Antibiotics That Block Translation Puromycin acts on both prokaryotic and eukaryotic cells. It has a structure similar to that of the 3′ end of the aminoacyl-tRNA carrier...
Increased protein requirements in elderly people: new data and retrospective reassessments. Am J Clin Nutr. 1994;60(4):501-509.PubMedGoogle ScholarCrossref 13. Koopman R, Verdijk L, Manders RJ, et al. Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the ...
Whole Body Protein Synthesis and Energy Expenditure in Very Low Birth Weight Infants C. CATZEFLIS, Y. SCHUTZ, J.-L. MICHELI, C. WELSCH, M. J. ARNAUD, AND E. JEQUIER Institute of Physiology, Faculty of Medicine, University of Lausanne, Luusanne [C.C., Y.S.,E.J.];Service of ...
Global muscle protein synthesis after acute exercise was assessed using the SUrface SEnsing of Translation (SUnSET) method as described previously16. Puromycin was dissolved in sterile saline (0.9% NaCl) and delivered via i.p. injection (0.02 μmol puromycin × g–1 body weight) 30 min pri...
The greater anabolic response to the EAA/protein composition was due to greater increases in whole-body protein synthesis with both doses, and a markedly greater suppression of whole-body protein breakdown in the high-dose group. Muscle protein FSR after beverage consumption reflected changes in ...
Protein synthesisis a costlybiochemical processaccounting for approximately 50% of the cell's energy, which is increased incancer cells[1]. Much ofprotein synthesisregulation occurs at the step ofmRNA translationinitiation. Briefly,40S ribosomal subunitsbind eukaryotic initiation factors (eIFs) 1, ...
Protein synthesis refers to the biological process whereby amino acids are assembled by peptide bonding into specific polypeptide sequences in accord with genetic blueprints encoded by deoxyribonucleic acid (DNA). From: Encyclopedia of Stress (Second Edition), 2007 ...
Importantly, a causal relationship between elevated translation and ASD-like behaviors has been recently established in mice. Deletion of the 4E-BP2-coding Eif4ebp2 gene or overexpression of eIF4E under the promoter of beta tubulin (βT-Eif4e) increases protein synthesis in the mouse brain and ...
Nanomaterials: a review of synthesis methods, properties, recent progress, and challenges. Mater. Adv. 2, 1821–1871 (2021). Article Google Scholar Lundqvist, M. et al. Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts. Proc. ...