Yonath MRC Laboratory of Molecular Yale University, Weizmann Instute of Biology, Cambridge, UK New Haven, CT, USA Science, Rehovot, Israel “for studies of the structure and funcon of the ribosome ” The ribosome translates the mRNA sequence into protein sequence The structure of the large and...
Biochemistry and structural biologyBioinformaticsGenome studiesThis chapter covers the general features of protein structure and recent advances in structural bioinformatics. The importance of the three-dimensional structure of the protein target in order to understand its mechanism of action as an aid for...
Proteins containing repetitive sequences are abundant in proteomes, fold in unusual non-globular structures, perform vital functions and are related to major health threats of the modern society. Along this line, the discovery of these domains, understanding of their sequence–structure–function relati...
These include helix hairpins and helical bundles, commonly found in class II bacteriocins such as the well-known food preservative nisin. AMPs with αβ structure often have disulfide bonds, such as those seen in plant defensins' cysteine-stabilized αβ (CSαβ) motif. All-β AMPs have ...
Each protein has a particular structure necessary to bind with a high degree of specificity to one or a few molecules and to carry out its function; thus, function is directly correlated to structure of the protein. Proteins make up about 50 percent of the dry weight of cells and are the...
2、They capture the structure, function, and evolutionary fitness of sequence variants 3、They can be enriched with prior knowledge and inform function predictions 4、They can revolutionize protein biology by suggesting new ways to approach design ...
Neurological and cardiovascular abnormalities occur in patients with severe genetic hyperhomocysteinemia and lead to premature death du... (展开全部) 我来说两句 短评 ··· 热门 还没人写过短评呢 我要写书评 Homocysteine in Protein Structure/Function and Human Disease的书评 ··· ( 全部0 条...
[17,18,19]. This review is focused on MLL1, since it is the most studied and involved in a number of chromosomal translocations causing 5–10% acute leukemia in children and adults with a poor prognosis [10,20]. We summarize the biology, structures, structure–function relationships and ...
ScienceDirect.com - Current Opinion in Structural Biology - Long-timescale molecular dynamics simulations of protein structure and function 来自 mendeley.com 喜欢 0 阅读量: 56 作者:K Lindorfflarsen,RO Dror,DE Shaw 被引量: 494 年份: 2009 ...
structure, function, and interactions Prediction of Protein Structures, Functions and Interactions focuses on the methods that have performed well in CASPs, and which are constantly developed and maintained, and are freely available to academic researchers either as web servers or programs for local ...