On account of its sensitivity to chirality, Raman optical activity (ROA), measured here as the intensity of a small, circularly polarized component in the scattered light using unpolarized incident light, is a powerful probe of protein structure and behavior. Protein ROA spectra provide information ...
PBxplore is a suite of tools dedicated to Protein Block (PB) analysis. Protein Blocks are structural prototypes defined by de Brevern et al. The 3-dimensional local structure of a protein backbone can be modelized as an 1-dimensional sequence of PBs. In principle, any conformation of any ...
Analyzing NovaFold Protein Structure Prediction Results In this video, learn how to use the NovaFold report and analysis views to analyze your protein structure prediction models, including how to examine predicted ligand binding sites, align experimental structures to the prediction model, and analyze ...
methods (e.g., BLAST)26. However, the top-performing CAFA methods typically rely strongly on manually-engineered features constructed from either text, sequence, biological networks, or protein structure31. In most cases, for newly sequenced proteins, or proteins of poorly studied organisms these f...
Fig. 4: Sequence and structure alignments allow analysis of conservation and flexibility. Comparison of L1 proteins from pentamers of HPV11 (cyan, PDB ID 2r5k [31]) and HPV18 (orange, PDB ID 2r5i [31]), using the Java Web Start “Structure Alignment” tool. Arrows indicate sites with...
0.3.2 Structure Database DatabaseDescription PDB The Protein Data Bank (PDB) is a database of 3D structural data of large biological molecules, such as proteins and nucleic acids. These data are gathered using experimental methods such as X-ray crystallography, NMR spectroscopy, or cryo-electron...
Analysis of these structural features is very important for understanding of structure-function relationships, for the design of potential inhibitors or proteins with improved functional properties. Here we critically review existing software tools specialized in rapid identification, visualization, analysis ...
Intact Protein AnalysisPoster NoteStructure Characterization and Differentiation of Biosimilar and Reference Products Using Unique Combination of Complementary Fragmentation MechanismsLife Science Mass Spec Intact Protein AnalysisPresentationCharacterization of mA...
CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures A Summary: The transport of ligands, ions or solve Kozlikova,Barbora,Sebestova,... - 《Bioinformatics》 被引量: 47发表: 2014年 The crystal structure of mycobacterial epoxide hy...
With the growth of protein structure data, the analysis of molecular interactions between ligands and their target molecules is gaining importance. PLIP, the protein–ligand interaction profiler, detects and visualises these interactions and provides data in formats suitable for further processing. PLIP ...