Primary Structure of Proteins. The linear sequence of amino acids constitutes a protein's primary structure. The sequence is written from the amino-terminal end (the first amino acid) to the carboxyl-terminal end (the same sequence in which the protein is synthesized). All properties of a pr...
The amino acids present in proteins differ from each other in the structure of their side (R) chains. The simplest amino acid isglycine, in whichRis a hydrogen atom. In a number of amino acids,Rrepresents straight or branchedcarbonchains. One of these amino acids isalanine, in whichRis th...
In subject area: Biochemistry, Genetics and Molecular Biology A loop, also called a coil, is a flexible segment of contiguous polypeptide chain that connects two secondary structure elements in a protein. From: Computational and Structural Biotechnology Journal, 2013 ...
Protein structure predictions are bioinformatic analyses that produce predicted protein structures automatically using the protein amino acid sequence. Protein structures are important because structural features can shed light on biological functions.
Intrinsically Disordered Proteins: The “Unstructural” Aspect of Structural Biology30 It has long been known that structural flexibility exists in proteins and aids in ligand binding. Nevertheless, the “structure–function paradigm”—that is, that proteins possess definitive three-dimensional structures...
Structural Biology Knowledgebase: a biologists resource for protein structure and sample informationThe Structural Biology Knowledgebase (SBKB, ) is a scientific search portal that returns comprehensive biological and methodological information about a protein sequence. Information related to 3D protein ...
Protein structure (Carolina biology readers no 34) second edition: By D C Phillips and A C T North. Published by Carolina Biological Supply Co and distributed by Packard Publishing Ltd. Chichester, Susses, UK. 1979. 1.35No abstract is available for this article....
In order to recognize the protein functions of proteins at a molecular level, it is sometimes necessary to determine their 3D structure. Accurately and reliably predicting structures from protein sequences is one of the most challenging tasks in computational biology2. Protein secondary structure ...
▲ Abstract:We present a mutagenesis strategy to arrest the RSV F protein in its pre-F state by blocking localized changes in protein structure that accompany large-scale conformational rearrangements. We generated a series of mutants and screened them in vitro to assess their potential for forming...
Structure alignment research has led to the discovery of homologues of novel protein structures. And, although many structure alignment tools have been developed, such as CE [4], DALI [5], VAST [6], MAMMOTH [7], FATCAT [8], and Vorolign [9], we wanted to provide a different perspecti...