Therefore, FAM134B gene may be performing a yet unidentified function in senescent cells. All in all, we have identified two FAM134B-encoded proteins that localize to the ER, the function and the senescence association of which need further investigation.Taş...
Our observations indicate that the senescence-associated SAG29 protein is associated with cell viability under high salinity and other osmotic stress conditions. We propose that the SAG29 protein may serve as a molecular link that integrates environmental stress responses into senescing process. 展开 ...
In conclusion, sweet potato SPCP3 is a functional, senescence-associated gene. Its mRNA and protein levels were significantly enhanced in natural and ... HJ Chen,DJ Huang,WC Hou,... - 《Journal of Plant Physiology》 被引量: 150发表: 2006年 Genes with homologies to known α‐galactosidases...
别名Cell senescence related gene complementation group B; Cellular senescence related protein 1; CSR; CSRB; MORF 4; MORF4; MORF4 protein; Mortality factor 4; SEN 1; SEN; Senescence (cellular) related 1; Senescence related cellular 1; Transcription factor like protein MORF4; MO4L1_HUMAN; Mort...
[174]. The resultant hypophosphorylated pRb repressed E2F target gene expression, contributing to cellular senescence and senescence-associated heterochromatin foci (SAHF) formation induced by activated oncogene H-Ras (H-RasV12) in human diploid fibroblasts WI38 [174]. This study provides further ...
et al. PRMT1 is recruited via DNA-PK to chromatin where it sustains the senescence-associated secretory phenotype in response to cisplatin. Cell Rep. 30, 1208–1222.e9 (2020). CAS PubMed Google Scholar Bajbouj, K. et al. Abstract 4711: PRMT5 selective inhibitor enhances therapeutic ...
Furthermore, age influences the senescence of cells and Boulestreau et al. recently demonstrated that mesenchymal-stem-cell-derived EVs are components of the senescence-associated secretory phenotype, i.e., proinflammatory cytokines and chemokines and tissue-damaging proteases and play a critical role ...
Phytohormones influence a range of events during the life cycle of plants beginning with seed germination and culminating in senescence and regulate them under different conditions, including biotic and abiotic stresses [66–75]. Exploration of various studies on plant hormonal regulation and G-prot...
We report here the positional cloning of Gpc-B1, a wheat quantitative trait locus associated with increased grain protein, zinc, and iron content. The ancestral wild wheat allele encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves ...
By genetically manipulating the senescence process, we provided a new method for converting most human fibroblasts into neural cells in only 1–2 weeks. Both ROCK and mTOR kinases are involved in senescence and proliferation processes, implicating that the reprogramming process may also be regulated ...