Lysine crotonylation has been discovered in histone and non-histone proteins and found to be involved in diverse diseases and biological processes, such as neuropsychiatric disease, carcinogenesis, spermatogenesis, tissue injury, and inflammation. The unique carbon–carbon π-bond structure indicates that ...
A total of 2106 crotonylated sites matched on 1006 proteins overlapping in three independent tests were identified, and we found three specific amino acids surrounding crotonylation sites in Pinellia ternata: K Conclusions:These results indicate that lysine crotonylation performs important functions in ...
Protein lysine crotonylation: past, present, perspective Article Open access 14 July 2021 Protein higher-order-structure determination by fast photochemical oxidation of proteins and mass spectrometry analysis Article 09 November 2020 References Murad, F. Cyclic guanosine monophosphate as a mediator ...
We reported an integrated database of Compendium of Protein Lysine Modifications (CPLM; http://cplm.biocuckoo.org) for protein lysine modifications (PLMs), which occur at active ϵ-amino groups of specific lysine residues in proteins and are critical for orchestrating various biological pr...
Furthermore, TgMYST-A, a histone lysine acetyl transferase, was found to improve histone acetylation and lactylation levels, which might have a synergetic effect on the differentiation of T. gondii. Notably, the anti-TgMYST-A antibody increased the levels of crotonylation and 2-hydroxyisobutyryl...
Hou1,2, Lan Zhou1, Jia‑Lei Li1, De‑Ping Wang1 and Ji‑Min Cao1* Open Access Abstract Crotonylation of proteins is a newly found type of post-translational modifications (PTMs) which occurs leadingly on the lysine residue, namely, lysine crotonylation (...
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development. Development. 2022;149(14). Hagihara H, Shoji H, Otabi H, Toyoda A, Katoh K, Namihira M, et al. Protein lactylation induced by neural excitation. Cell Rep. 2021;37(2):...
Indeed, we have shown that a few other short-chain acyl-CoAs can serve as precursors of lysine acylation, such as lysine propionylation, lysine butyrylation, and lysine crotonylation (Chen et al., 2007, Tan et al., 2011). Download: Download high-res image (144KB) Download: Download ...
LightGBMMulti-feature fusionSMOTELysine crotonylation is an important protein post-translational modification, which plays an important role in the process of ... Y Liu,Z Yu,C Chen,... - 《Analytical Biochemistry》 被引量: 0发表: 2020年 Fertility-LightGBM: A fertility-related protein prediction ...
(19) first identified histone lysine crotonylation (Kcr) in histone lysine, which is enriched at the transcriptional initiation site of specific genes in testis, indicating that histone crotonylation could be used as a marker for the active transcription of sex chromosome–related genes. After that ...