The genes coding for the human fragile X proteins (FMRP isoform 1 NCBI Reference Sequence: NP_002015.1, FXR1P isoform 2: NP_001013456.1, and FXR2P NP_004851.2) were introduced through Ligation Independent Cloning into the pMCSG9 vector r(DepNliAcaStUionp,laasnmdiadmrpepicoilsliitnorryes)...
immunizationgoatA previous study identified that isoform 2 (Hcftt-2) of the 14-3-3 protein of Haemonchus contortus (H. contortus) could suppress immune functions of goat peripheral blood mononuclear cells (PBMCs) and might be a potential vaccine target, as neutralization of the protein function...
International Journal of Molecular Sciences Article Modulation of Protein Quality Control and Proteasome to Autophagy Switch in Immortalized Myoblasts from Duchenne Muscular Dystrophy Patients Marion Wattin, Loïc Gaweda, Pascale Muller, Mathieu Baritaud, Charlotte Scholtes, Chloé Lozano, Kathrin Gieseler ...
However, the results of this experiment indicate that the decrease in the expression of slow isoform of MyHC after the completion of the initial stage of hindlimb unloading is determined not by AMPK, but by some other mechanisms, for example, via inhibition of the calcineurin/ Nuclear factor of...
Furthermore, an age-dependent loss in sarcoplasmic reticulum Ca2+-ATPase isoform 2a activity was also shown as a result of 3-nitrotyrosine accumulation in limb muscles of senescent rats [107]. Moreover, limb muscles from senescent mice (18 months old) also exhibited a reduction in the function...
Association of LOXIN, a new functional splicing isoform of the OLR1 gene, with severity and prognostic localization of critical coronary artery stenoses. J. Cardiovasc. Med. 2014, 15, 391–396. [CrossRef] [PubMed] 30. Waterworth, D.M.; Li, L.; Scott, R.; Warren, L.; Gillson, C...
The α1β1 isoform is the main Na,K-ATPase isozyme, which provides the driving force for Na+ reabsorption. Diverse α and β isozyme combinations are present depending on the tissues and cell types [12]. The γ-subunit, often known as FXYD2 protein, is mainly expressed in the kidney. ...