Burgess GM (1992) Analysis of protein kinase C function. In: Neuromethods, Vol. 20: intracellular messengers Boulton A, Baker G, Taylor C (eds), pp 231-271. New Jersey: Humana Press.Burges, G. M. (1992). Analysis of protein kinase C functions. Neu- romethods, 20, 231-271....
具体来说，Protein Kinase C (530-558)可能通过以下几种机制抑制破骨细胞的骨吸收：首先，它可能通过激活PKC来抑制破骨细胞前体的分化和融合，从而减少破骨细胞的数量；其次，它可能通过调节破骨细胞内的信号转导途径，抑制其分泌降解骨基质的酶和酸性物质；最后，它还可能通过促进破骨细胞的凋亡来降低其活性。这些...
Protein Kinase C Isozyme Panel 产品说明书 Protein Kinase C Isozyme Panel human, recombinant Product Code P 6862 Storage Temperature −70 °C Synonym: PKC Control Panel Product Description The Protein Kinase C Isozyme Panel contains nine isozymes of protein kinase C. Each isozyme is a human ...
Iconography : Protein kinase Cδ functions downstream of Ca2+ mobilization in FcεRI signaling to degranulation in mast cells (2004). Protein kinase cδ functions downstream of Ca2+ mobilization in FcεRI signaling to degranulation in mast cells. Journal of Allergy and Clinical... SH Cho,CH ...
Members of the protein kinase C (PKC) family of multifunctional serine/threonine phosphorylating enzymes are believed to play a role in regulating cellular differentiation and proliferation in many cell types. In the present study, we examined the expression of PKC isoforms in non-transformed (BMRPA...
[名词解释] protein kinase C,PKC (蛋白激酶C) 相关知识点: 试题来源: 解析 是G蛋白偶联受体系统中的效应物,在非活性状态下是水溶性的,游离存在于胞质溶胶中,激活后成为膜结合的酶。蛋白激酶C的激活是脂依赖性的,需要膜脂DAG的存在,同时又是Ca2+依赖性的,需要胞质溶胶中Ca2+浓度的升高。当DAG在质膜中出现时...
onprotein kinase Cfunction reveals a few defined themes in addition to the general involvement in cell growth and proliferation. Notably, animals deficient in protein kinase C isozymes are deficient in adaptive responses. For example, mice lacking protein kinase C ɛ have reduced anxiety and have...
Structural basis of protein kinase C isoform function 2008, Physiological Reviews View all citing articles on Scopus * This research was supported by National Institutes of Health Grant HL52141. The costs of publication of this article were defrayed in part by the payment of page charges. This...
[名词解释] protein kinase C system,PKC system (PKC系统) 相关知识点: 试题来源: 解析 由于该系统中的第二信使是磷脂肌醇,故此这一系统又称为磷脂肌醇信号途径(phosphatidylinositol signal pathway)。 在这一信号转导途径中,膜受体与其相应的第一信使分子结合后,激活膜上的Gq蛋白(一种G蛋白),然后由Gq蛋白激活...
中文名称: 蛋白激酶C抑制剂 Protein Kinase C Translocation Inhibitor单字母: H2N-LSETKPAV-OH三字母: H2N-Leu-Ser-Glu-Thr-Lys-Pro-Ala-Val-COOH氨基酸个数: 8分子式: C37H65N9O13平均分子量: 843.96精确分子量: 843.47等电点(PI): 6.41pH=7.0时的净电荷数: -0.02平均亲水性: 0.3疏水性值: -0.09外观...