comprising both protein assays and protein standards that make protein quantification easy, fast, and accurate. Pierce Dilution-Free products allow you to minimize tedious dilutions and pipetting errors in your protein assays, delivering accurate results while reducing assay setup time by up to 80%....
The following tables provide information to prepare a set of protein standards for a standard curve for common BCA assay and Bradford assays. To proceed dilute the contents of a 1 mL BSA standard (2 mg/mL) into several clean v...
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Protein half-life The time required for the amount or concentration of a protein to be reduced by 50% under physiological conditions. It is a measure of the propensity of a protein to be degraded by the ubiquitin–proteasome system (UPS). Proteins with short half-lives are rapidly degraded ...
For example, we measured a half-life of ~70 s for mStayGold E138D compared to 11 s for sfGFP (Supplementary Fig. 12a). Superior photostability of StayGold and mStayGold was also observed under widefield illumination with a metal halide source (Supplementary Fig. 12b). While testing ...
Half-life extension Manufacturability improvement Removal of high risk post-translational modifications Reduction of aggregation hotspots Improvement of stability Once variants have been designed, they can be expressed in a program tailored to your specific needs. Our locations Locations where this service ...
6.5.2Protein-based vaccine This type of vaccine is developed using theamino acid sequenceof a truncated or whole cancer antigen protein, which has a longer amino acid sequence than peptides (Table 2). This vaccine enables the approval, processing, and presentation of variousmajor histocompatibil...
On fibers that were 6 or 9 microns wide -- the typical size of fibers in tumors -- half the breast cancer cells elongated and slid around the cells they collided with. Conversely, 99 percent of the normal breast cells did an about face. ...
99 The compound was well absorbed, showed dose-proportional exposure, and had a plasma half-life of between 13 and 16 h. In general, imaitinib was well tolerated; the MTD was not reached, and the most common adverse events were nausea, myalgias, edema, and diarrhea.100 Encouragingly, ...
Cirrito JR, May PC, O’Dell MA, Taylor JW, Parsadanian M, Cramer JW, Audia JE, Nissen JS, Bales KR, Paul SM, DeMattos RB, Holtzman DM (2003) In vivo assessment of brain interstitial fluid with microdialysis reveals plaque-associated changes in amyloid-β metabolism and half-life. J ...