Another emerging biomarker is glycated albumin which has demonstrated utility in situations where HbA1c cannot be used. Other proteins undergo glycation as well thus impacting cellular function, transport and immune response. Accordingly, these glycated counterparts may serve as predictors for diabetic ...
Glycation is a non-enzymatic post-translational modification (PTM) that is correlated with many diseases, including diabetes, cancer and age-related disorders. Although recent work points to the importance of glycation as a functional PTM, it remains an
[Oxidative stress and protein glycation in diabetes mellitus]. Ann Biol Clin (Paris) 64, 309–314 (2006). 39. Lapolla, A., Molin, L. & Traldi, P. Protein glycation in diabetes as determined by mass spectrometry. Int J Endocrinol 2013, 412103, doi: 10.1155/2013/412103 (2013). 40. ...
Glycation is a non-enzymatic post-translational modification (PTM) that is correlated with many diseases, including diabetes, cancer and age-related disorders. Although recent work points to the importance of glycation as a functional PTM, it remains an
et al. Correction: Correlation between circulating advanced glycation end products and thioredoxin-interacting protein levels and renal fat content in type 2 diabetes mellitus patients. Diabetol Metab Syndr 16, 198 (2024). https://doi.org/10.1186/s13098-024-01426-5 Download citation Published17 ...
Type II Diabetes mellitus, Kurus’s etc. Challenges lie in understanding the complex mechanism of protein misfolding and its correlation with clinical evidence. It is often understood that due to the slowness of the process and its association with ageing, timely intervention with drugs or preventiv...
Diabetology Fructose with an bound amine group, the serum levels of which reflect the degree of glycation of serum proteins; fructosamine levels reflect glycemic control over a period of 2-3 wks. See Glycosylated hemoglobin. McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGra...
Diabetes mellitus was induced in rats by a single intraperitoneally (IP) injection of alloxan (Sigma, USA) at a dose of 120 mg/kg dissolved in sterile 0.9% saline [18]. Five days after the injection of alloxan, the blood glucose level of the rats was measured from tail vein. DM was ...
In conclusion the results from the present study suggest that Indian subjects with family history of type 2 diabetes are associated with insulin resistance and enhanced glycation of proteins, but with no evidence of beta cell defect. 展开
and anti-protein glycation activities. The strong binding affinities of some of the identified compounds could be responsible for the inhibitory potential of the extracts.I. gabonensisstem bark could be further explored as a natural remedy for the treatment of diabetes mellitus and its complications....