These formulations provide unexpected and considerably greater chemical stability than when compared to GLP-1-Fc fusions at a pH outside the described ranges. The formulations comprising a GLP-1-Fc fusion are useful in treating diabetes, obesity, irritable bowel syndrome and other conditions that ...
此外,GLP-1蛋白可以通过影响 LH、TSH、CRH、催产素和抗利尿激素的分泌来调节下丘脑-垂体轴 (HPA) [5]。 GLP-1 蛋白通过减少炎症细胞因子的产生和免疫细胞在组织中的浸润,对胰岛和脂肪组织具有抗炎作用,此外在一些慢性炎症疾中,包括 1 型和 2 型糖尿病、动脉粥样硬化、神经退行性疾病、非酒精性脂肪性肝炎、糖...
GLP-1/GCG Protein, Human (HEK 293, His) 英文名称: rHuPro-glucagon/GCG, His 总访问: 46 国产/进口: 进口 半年访问: 3 产地/品牌: MedChemExpress(MCE) 产品类别: 生化试剂 规格: 10 μg; 50 μg 最后更新: 2024-11-4 货号: HY-P70239 CAS 号: 参考报价: 1702; 5100 立即询价 电话咨询...
产品活性:GLP1R 蛋白是胰高血糖素样肽 1 (GLP-1) 的 G 蛋白偶联受体,与配体结合后会激活腺苷酸环化酶并增加 cAMP 水平。这种相互作用严重调节胰岛素分泌,影响与 GLP-1 信号传导相关的细胞反应和代谢过程。GLP1R 蛋白, Human (HEK293, N-His, C-Myc) 是重组的 GLP1R 蛋白,由 HEK293 表达,带有 C-Myc,...
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GLP-1 analog formulations The present invention relates to formulations of a lipid based controlled-release matrix, a polyhydroxy component and a bioactive agent. Such formulation are useful in the delivery of the bioactive compounds. The invention also relates t......
中文名称:胰高血糖素样肽-1蛋白 中文同义词:胰高血糖素样肽-1蛋白 英文名称:GLP-1 Protein 英文同义词:GLP-1 Protein CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览GLP-1 Protein国外供应商中国供应商 GLP-1 Protein推荐供应商 ...
GLP-1 receptor Protein kinase A Hyperglycemia Small ubiquitin-related modifier 1. Introduction Incretins are peptide hormones secreted by intestinal endocrine cells in response to nutrient stimulation [1]. At the β-cells of pancreatic islets of Langerhans, incretins act to enhance insulin synthesis ...
Human primary monocytes/macrophages were incubated with native GLP-1 (nGLP-1) or GLP-1 agonist liraglutide to evaluate their effect on ox-LDL uptake and the expression of scavenger receptors (SRs), such as SR-A, CD36, and lectin-like ox-LDL SR-1, in this process. Our study showed a ...
The glucagon-like peptide 1 (GLP-1) analog exendin-4 attenuates endothelial ER stress, but the detailed vasoprotective mechanism remains elusive. The present study investigated the beneficial effects of exendin-4 against HHcy-induced endothelial dysfunction. Exendin-4 pretreatment reversed homocysteine-...