Viviana Scognamiglio,Maria Staiano,Mose’ Rossi,Sabato D’Auria.Protein-Based Biosensors for Diabetic Patients[J]. Journal of Fluorescence .2004(5)Scognamiglio V,,Staiano M,Rossi M,et al.Protein-based biosensors for diabetic patients. Journal of Fluorescence . 2004...
Here, we show that thioredoxin-interacting protein (Txnip), a member of the arrestin protein superfamily and one of the most strongly induced proteins in diabetic patients, regulates PDI activity and UPR signaling. We found that Txnip binds to PDIs and increases their enzymatic activity. Genetic ...
36,40,41,42,43, including the loss of cell surface proteoglycans35,36,40,41,42,43and expression of angiogenesis inhibiting growth factors44. Diabetic patients in particular have reduced recruitment of stem cells to ischemic regions, circulating EPCs, and endothelial cell function45,46. We ...
G protein-coupled receptors (GPCRs) can affect insulin action, insulin secretion and β-cell expansion, and certain GPCRs have emerged as potential drug targets for the development of anti-diabetic therapeutics. Decreased insulin sensitivity is a major metabolic defect in the great majority of indiv...
Clinical Application of the Nonenzymatic Glycation of Hair Protein in Diabetic Patients The assay of furosine, an acid-hydrolysis product derived from fructose-lysine in glycated protein, was used as a specific method for determining Amadori c......
Manders RJF, Praet SFE, Meex RCR, Koopman R, de Roos AL, Wagenmakers AJM, Saris WHM, van Loon LJC (2006b) Protein hydrolysate/leucine ingestion reduces the prevalence of hyperglycemia in Type 2 diabetic patients. Diabetes Care 29:2721–2722 Article CAS Google Scholar Manton DJ, Cai F, ...
Body Image as a Mediator Between Gender and Quality of Life Among Patients With Diabetic Foot Ulcers in Indonesia Introduction Foot ulcers cause women in Indonesia to lose opportunities to participate in religious and cultural activities due to the inability to wear ce... MMEP Ni,D Yasmara,MF ...
Conversely, diabetic patients display obvious abnormalities in protein glycosylation, including chitosidase (chit1)13 and immunoglobulin G (IgG)14. N-glycosylation map has been used as a biomarker to monitor the progression of early T2DM15. Therefore, we speculate that T2DM contributes to the ...
(ERK-1 and -2), c-jun N-terminal kinase, and p38; these components, collectively referred to as thestress-activated protein kinases,have been shown to be elevated insuralnerve biopsiesof diabetic patients with advancedneuropathy.134In the STZ rat, JNK and p38 are transported from the ...
the difference was not significant( P 0. 05).Conclusions Changes in the status of blood HCT index has a positive significance in the diagnosis of the degree of dehydration in patients with acute diarrhea,WBC C-reactive protein values of the indicators for clinical treatment and provide a ...