Protein folding and stability: What can we learn from high pressure?protein foldingpressure-jump relaxationactivation volumetransition stateThe relationships between the amino acid sequence of proteins and their structural and functional specificity have yet to be elucidated, as do the determinants for ...
Protein Stability and Folding 作者:Shirley 出版社:Humana Pr Inc 出版年:1995-3 页数:388 定价:$ 213.57 装帧:Pap ISBN:9780896033016 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到
of these proteins is quite difficult due to problems with their stability. This collection gives - in the form of tables - protein stability data for various temperatures and solvents. These data are most useful for the development of protein folding and the improvement of biotechnological stabil....
15.All-atom Simulations of Protein Folding and Stability;蛋白质折叠和稳定性的全原子模拟研究 16.Discontinuous Molecular Dynamics Simulations of Protein Folding Based upon All-atom Models;蛋白质折叠的全原子非连续分子动力学模拟 17.The garbage in question is abnormally folded proteins.问题出就出在这些异常...
We discuss the consequences of these findings regarding protein folding stability and solvation in crowded solutions through a structural analysis of the -value or the change in free-energy difference of a macromolecule in solution with respect to the concentration of a third component. 展开 ...
Protein Folding and Stability Filomena A. Carvalho, ... Nuno C. Santos, in Archives of Biochemistry and Biophysics, 2013 Protein folding Protein folding, although thoroughly researched, is not yet fully understood [2–10], with its mechanism(s) remaining one of the most elusive problems in bio...
To date, correlations between oxidation rates and protein stabilities have been reported for a few individual proteins (42, 43). However, the general correlation between folding stability and methionine oxidation rates has not been studied on a proteome-wide scale. We used mass spectrometry (MS)-...
The hydration of nonnative states is central to protein folding and stability but has been probed mainly by indirect methods. Here we use water 17O relaxat... VP Denisov,BH Jonsson,B Halle - 《Nature Structural Biology》 被引量: 387发表: 1999年 Cooperative water filling of a nonpolar protei...
Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often involves stepwise establishment of regular secondary and supersecondary structures, namely α-helices and β-sheets...
Acquisition of mutations is central to evolution; however, the detrimental effects of most mutations on protein folding and stability limit protein evolvability. Molecular chaperones, which suppress aggregation and facilitate polypeptide folding, may alleviate the effects of destabilizing mutations thus promot...