Recent trends in protein and peptide drug delivery system. Asian Journal of Pharmaceutics, 2009: 2(3); pp 69-75.Gupta H. and Sharma A. Recent trends in protein and peptide drug delivery systems. Asian J. Pharm, 2009; 3(2) : 69-75....
Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems 克服生物可降解药物传递系统中蛋白质和多肽不稳定性的策略 相关领域 药品 药物输送 药理学 体内 控制释放 纳米技术 化学 医学 生物技术 生物 材料科学 网址 https://doi.org/10.1016/j.addr.2023.114904 ...
Systemic injection into blood vessels is the most common method of drug administration. However, targeting drugs to the heart is challenging, owing to its dynamic mechanical motions and large cardiac output. Here, we show that the modification of protein and peptide therapeutics with tannic acid—a...
Significant advancements in peptide designs strategies, detection methods/assays, and developmental strategies have resulted in achieving efficacious peptides with better drug-like properties including oral bioavailability. Abstract Immune system regained the attention of oncologists and has entered the mainstrea...
Once engineered, intracellular bacteria can efficiently deliver proteins to tumors. Current delivery methods, including nanoparticles, cell-penetrating peptides, and antibody drug conjugates have limited efficacy because of (1) poor uptake into cells, (2) lack of specificity to cancer cells, (3) degr...
This challenge has been successfully met in the formulation of several peptide and protein drugs using the DepoFoam™, multivesicular lipid-based drug delivery system. DepoFoam technology consists of novel multivesicular liposomes characterized by their unique structure of multiple non-concentric aqueous ...
The electrophoresis patterns of peptide showed that the molecular weight was much smaller than soy protein and concentrated in a very small range. The molecular weight distribution of the soy peptide was analyzed using a 1260 Infinity II LC system with a TSK-GEL G2000SWXL (5 μm, 7.8 × 300...
Peptide and protein drug delivery. Edited by Vincent H. L. Lee. Marcel Dekker: New York. 1991. 891 pp. 25 × 18 cm. ISBN 0‐8247‐7896‐0. $150.00Peptide and protein drug delivery. Edited by Vincent H. L. Lee. Marcel Dekker: New York. 1991. 891 pp. 25 × 18 cm. ISBN 0‐82...