Disclosed are human interleukin-1 'beta' converting enzyme like apoptosis proteases-1 and 2 and DNA (RNA) encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and antibodies and antagonists/inhibitors against such polypeptides. Also provided ...
An enzyme and enzymatic procedures for cleaving the -secretase cleavage site of the APP protein and associated nucleic acids, peptides, vectors, cells and isolates and assays are described. An enzyme that cleaves the alpha -secretase site of APP is provided also. Further provided is a modified ...
The antibody-antigen interactions observed in this complex provide a structural basis for understanding the origin of the broad reactivity of mAb-1696 for the HIV-1 and HIV-2 proteases and their respective N-terminal peptides. Conclusion: A possible mechanism of HIV-protease inhibition by mAb1696...
The major fraction of proelastase 2 binding activity, which eluted with the major protein peak, was further purified by DEAE-cellulose chromatography at pH 8.8 and at pH 6.5 and by gel filtration on Sephadex G-100. This activity was found to co-purify with α 1-protease inhibitor. ...
While the vast majority of HIV/AIDS cases in the world are due to HIV-1, HIV-2 infection must also be addressed. HIV-2 is endemic to Western Africa, and has also appeared in European countries such as Portugal, Spain, and Estonia. Current protease inhibitors have not been optimized for ...
041 Simple and sensitive assays to detect autoantibodies against alpha 2 macroglobulin-like 1 in paraneoplastic pemphigus sera PNP is characterized by the presence of autoantibodies against a broad spectrum of desmosomal components, additionally more than 50% of patients also have antibodies against the...
OBJECTIVES: A new approach to estimation of IgA subclass levels and IgA1/IgA2 ratio using enzymatically active and inactive forms of Neisseria meningitidis IgA1 protease was developed. RESULTS: The approach was tested using the sera of healthy volunteers and patients with meningococcal meningitis. The...
蛋白酶1(PROTEASE 1, ACHROMOBACTER LYTICUS RECOMBINANT) CBNumber: CB74678772 分子式: 分子量: 0 MOL File: Mol file 化学性质安全信息用途供应商0 蛋白酶1(PROTEASE 1, ACHROMOBACTER LYTICUS RECOMBINANT)化学性质 安全信息 蛋白酶1(PROTEASE 1, ACHROMOBACTER LYTICUS RECOMBINANT)性质、用途与生产工艺 ...
Gustatory innervation and bax-dependent caspase-2: participants in the life and death pathways of mouse taste receptor cells observed that taste receptor cells were selectively immunopositive for the bcl-2 family death factor, Bax, and for the protease Caspase-2 (Nedd2/Ich1)... Q Zeng,A Kwan...
HIV-1SemenHIV protease gene sequenceProtease inhibitorsPhylogenetic analysisIt is well established that HIV is found in semen, either as cell-free or cell ... RA Byrn,AA Kiessling - 《Journal of Reproductive Immunology》 被引量: 78发表: 1998年 A combination of nucleoside analogues and a protea...