HIV-1 protease is an enzyme produced by the HIV virus. Two identical chains of 99 amino acids form the enzyme. In each chain, amino acids 25, 26 and 27 in the sequence form part of the active site. Which orders of protein structure control the shape of the active site? A. primary,...
2011. A key enzyme in the biogenesis of lysosomes is a protease that regulates choles- terol metabolism. Science 333:87-90.K. Marschner, K. Kollmann, M. Schweizer, T. Braulke, S. Pohl, A key enzyme in the biogenesis of lysosomes is a protease that regulates cholesterol metabolism, ...
A soluble hemagglutinin/protease produced by Vibrio cholerae, which has previously been shown to hydrolyze fibronectin and ovomucin and to cleave lactoferrin and the A subunit of the heat-labile enterotoxin of Escherichia coli, appears to be a zinc metalloendopeptidase. Both its hemagglutinative and pr...
protease. The encoded protease functions in the ectodomain shedding of tumor necrosis factor-alpha, in which soluble tumor necrosis factor-alpha is released from the membrane-bound precursor. This protease also functions in the processing of numerous other substrates, including cell adhesion proteins, ...
b, Knockdown of HRI is protective for cells in which the mitochondrial ribosomal protein MRPL17 is depleted, but sensitizes cells in which the mitochondrial protease LONP1 is depleted. HEK293T cells were co-transduced with a lentiviral construct expressing GFP and an sgRNA that targets HRI, and...
(residues ca. 608–630; ZipN is 798 residues long). Whereas different topology predictions give inconsistent results, our results of BACTH analysis showing positive interactions with T25-ZipN strongly suggests a cytoplasmic localization of the ZipN N-terminus since, to reconstitute an active enzyme,...
Evidence that hatching enzyme of the sea urchin Strongylocentrotus purpuratus is a chymotrypsin-like protease 来自 NCBI 喜欢 0 阅读量: 26 作者:LL Post,R Schuel,H Schuel 摘要: The sea urchin blastula secretes a hatching enzyme (HE) that dissolves the fertilization envelope. HE was collected ...
Plasma insulin was measured by an enzyme-linked immunosorbent assay kit from Crystal Chem (Elk Grove Village, IL). Total TG, total cholesterol, and alanine aminotransferase were examined by kits from Stanbio (Kolkata, IN). Blood glucose was determined by glucometer Accu-Chek, Indianapolis, IN....
Protein phosphatase 2A (PP2A), a conserved serine/threonine phosphatase, plays an essential role in various cellular functions in eukaryotic organisms. The PP2A holoenzyme comprises a heterodimeric core enzyme, consisting of a 65-kDa scaffolding subunit (PP2A-A) and a 36-kDa catalytic subunit (PP2A...
Benzaldehyde, the simplest aromatic aldehyde, is one of the most wide-spread volatiles that serves as a pollinator attractant, flavor, and antifungal compound. However, the enzyme responsible for its formation in plants remains unknown. Using a combination of in vivo stable isotope labeling, classica...