But a number of benign conditions will also cause elevated PSA levels and, conversely, prostate cancer has been diagnosed in the absence of raised PSA. We analyze one of the most extensive data sets currently available for longitudinal PSA readings, obtained by an historical prospective study of ...
PSA readings in the study are validated in a central laboratory to exclude inter-site variations. The results found a Spearman’s agreement of 0.95 between study sites (Bancroft et al, 2014). Statistical considerations PSA velocity (PSAV) has been used as a marker to inform decisions about bi...
Additionally, 15 benign prostatic hyperplasia (BPH) samples from 13 patients who underwent TURP without known presence of prostate cancer, and 14 prostate Bx cores, were collected between April 2006 and February 2009 from 14 patients with elevated PSA readings, but no evidence of prostate cancer ...
PSA levels, Gleason Score, and pT stage are established clinical parameters in prostate cancer prognosis. Using the Cox model, we aimed to determine the independent effect of each of these factors on the time to biochemical recurrence, thereby gaining a more comprehensive understanding of their ...
(B) Prostate-specific antigen levels of 301 men as depending on increasing age. Relation of Prostate Volume to Prostate-Specific Antigen Level Fig. 25.8A shows the prostate volumes of 301 men with urologic problems as related to the rank order of PSA levels in increasing sequence. Any pattern...
Further complicating the screening process is that several medications and a number of other modifiable factors may alter the results of the PSA lab test, leading to inaccurate readings that may overestimate or underestimate your risk of having prostate cancer found on a biopsy....
At 2 years, there was no difference between low- and intermediate/high-risk patients, with PSA readings of 0.44 and 0.50 ng/ml, respectively (p = 0.63). A benign PSA bounce – a PSA uptick and a subsequent decline to nadir – was observed in 12% of the 71 SBRT-monotherapy patients ...
Many urologists recommend taking a bit of time and having 2 or more PSA readings before moving forward with a biopsy. Also talk to your Doctor about doing more than just the standard PSA test, for example, testing for ‘Free PSA’ which can support the standard total PSA test. If the st...
In clinical practice, PCa is confirmed or excluded by transrectal ultrasound-targeted biopsy, based on the results of digital rectal examination or serum prostate-specific antigen (PSA) levels4, and perfusion analysis by CETRUS5. However, recent findings have demonstrated that CETRUS is of limited...
st-tests (notified by *) to correlate CCR3 expression to non-ordered categorical variables (for example, presence or not of emboli or biochemical recurrence). The biochemical recurrence, as defined by the European Association of Urology guidelines, corresponded to two PSA readings >0.2 ng ...