With regular PSA readings ranging from 9-12, I opted for “watchful waiting” believing that I could figure out a way to self-medicate but later with increasingly persistent prostate discomfort especially on sitting and pressure pain on one side of the gland some decisions had to be made. Sub...
Budi, in his mid-sixties, had problems with urination in 1996. The doctor suspected BPH – Benign Prostatic Hyperplasia. He was prescribed Proscar. This medication was effective and Budi took this for about 2 years. With the medication, his PSA readings were normal. In 2008, Budi was prescri...
for their prostate-specific antigen (PSA), a serine protease protein biomarker secreted by the prostate [13]. Repeated PSA readings are taken during patient check-ups. Patients present at diagnosis with elevated PSA levels, which decrease upon starting of HT and radiotherapy (RT). Thus, increased...
More than 20 per cent had PSA readings high enough to prompt a biopsy. However in the follow up reading half had their PSA levels return to normal. The recommendation? Dont rely on one reading. Have another at least two weeks later. (Ed: and several more!! The Fred Hutchinson Cancer ...
a, bIHC staining (a) and relative intensities (b) of the NGF and CHRM4 of a prostate cancer TMA consisting of normal tissues (n = 16), adenocarcinomas with a Gleason score of ≤7 (n = 81), adenocarcinomas with a Gleason score of ≥8 (n = 19), and SCNCs (n =...
If we had readings 2, 4, 3, 5, 1, 6, and wanted a moving mean of 3, m3 would be (2 + 4 + 3)/3 = 3 and m4 would be 3 + (5 – 2)/3 = 4. The values of a moving median of 3 would be 3, 4, 3, 5. There are missing elements at the beginning unless they are ...
AGR2 expression is increased in prostate cancer cells (and cells of high-grade prostatic intraepithelial neoplasia, PIN) compared with the normal counterpart luminal epi- thelial cells.3–6 CD10, in contrast, is decreased in cancer cells, although about 30% of tumors express CD10.7–9 Tumors ...
low PSA levels. It works best when the PSA is close to 1.0 ng/mL, but it has detected prostate cancer about 30% of the time at PSA levels in the 0.2–0.3 ng/mL range. I went for this PSMA PET scan in January when my PSA was 0.37 ng/mL, and the scan failed to detect ...
Data were normalized to readings from siNC treatment on day 1 and plotted as relative cell viability to generate growth curves. Alternatively, for CRISPR sgRNA growth assays, cells were treated as described above for target gene inactivation and seeded into a 96-well plate at 2500 cells per ...
MED19, a component of the mediator complex and a co-regulator of the androgen receptor (AR), is pivotal in prostate cancer cell proliferation. MED19 has two isoforms: a full-length “canonical” and a shorter “alternative” variant. Specific antibodies