We collapsed the none and 1 to 3 ejaculation categories because of insufficient numbers of participants in the none category.Case Ascertainment On each follow-up questionnaire, we asked participants whether they had received a diagnosis of prostate cancer during the prior 2 years. For men who ...
their results showed a significant improvements in comparison to the normal CNN approaches. Coarse-to-fine segmentation was used by Jia et. al.32where they used an atlas registration, followed by a CNN-based pixel classification and finally an ensemble learning for fine segmentation, their results ...
[Post-radiation therapy], the radiation oncology literature uses the Phoenix criteria definition [of a PSA increase of at least 2 ng/mL above the post-radiation nadir]. However, some of these patients become biochemically recurrent and possibly metastatic at lower numbers. [We need to make]...
Second, the inclusion of numbers and rates in our DCE might have caused problems with understanding the choice task. However, 93% of the respondents passed the rationality test that was included in the questionnaire, and 76% of the respondents did not find the DCE questions difficult. We ...
Numbers refer to the percent sequence identity in the domains where AR is 100%. B, inter- and intradomain interaction in hAR; the intrinsically disordered (ID) NTD contains the FQNLF motif and the AF1 region, which contains Tau-1 and Tau-5; DBD, DNA-binding domain and the LBD, ligand...
men with disease confined to the prostate or nearby tissues. Many men live much longer. When the disease has spread to distant areas, that figure drops to 31%. But these numbers are based on men diagnosed at least 5 years ago. The outlook may be better for men diagnosed and treated ...
(ii) replication-competent adenoviruses have the potential to replicate to high copy numbers, thereby resulting in significantly greater therapeutic gene expression in vivo; and (iii) replication-competent adenoviruses have greater potential to spread locally and therefore could infect a greater number of...
Mutations of the MEN1 gene predispose to multiple endocrine neoplasia type 1 (MEN1) syndrome. Our group and others have shown that Men1 disruption in mice recapitulates MEN1 pathology. Intriguingly, rare lesions in hormone-dependent tissues, such as pros
Comparing the localized copy numbers of the mutant 5′-UTR on a per-patient basis, we observed no increase in copy number losses as a result of having a functional 5′-UTR mutation (Supplementary Fig. 9b). Together, these findings demonstrate that 34.8% of mutated 5′-UTRs harbor ...
(mean log2RNA abundance difference = 0.075, 95% CI: 0.070–0.079,p = 1.13 × 10−2, Mann–Whitney U test; Fig.S5). Only four patients in the Gerhauser cohort withZNRF3loss had available RNA abundance data, but there was a trend toward decreased ZNRF3 RNA abundance relative...