Stage 3 prostate cancerThis is an advanced stage of prostate cancer in which PSA levels are 20 or higher. The tumor is growing and likely to spread at a rapid rate. This stage also has three substages, including:Stage IIIA: The cancer is spread beyond or on both sides of the prostate ...
Prostate cancer is a heterogeneous disease that exhibits a range of clinical behaviors, from indolent, slow-growing tumors to aggressive, fast-growing tumors with lethal progression. Although most tumors follow an indolentclinical courseand may not cause morbidity even if left untreated, most clinically...
But only 1 in 36 people who have prostate cancer die from it. That's because most prostate cancers are diagnosed in older people in whom the disease is more likely to be slow-growing and non-aggressive. Most of them eventually pass away fromheart disease,stroke, or other causes -- not ...
Generally speaking, the higher your Gleason score, the more aggressive the cancer. That means it’s more likely to grow and spread to other parts of your body. Doctors use this information, along with the stage of the cancer, to choose the best treatment for you. Staging Prostate Cancer Wh...
3c). The faster growing and more aggressive tumor behaviors were identified grossly in representative 6-, and 10-month-old TripleTg mice, featuring multiple tumors in different prostatic lobes, local invasion into seminal vesicles, and multiple metastatic tumor lesions (Fig. 3d). Pathological ...
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being the most aggressive cancer cell type. The Gleason score is based on the sum of these two numbers (tissue grade and cell type grade). A Gleason score of 5 + 5 = 10 indicates a highly aggressive prostate tumor while a low score (2 + 2 = 4) indicates a less aggressive cancer. ...
Most prostate cancers are slow growing and relatively benign, and the patient will most likely die from another cause before the cancer progresses. There is, however, a more aggressive subset of highly invasive and fast-growing prostate tumors. These tumors require aggressive initial treatment to ...
The prostate cancer condition center is a comprehensive resource for clinical news and expert insights on prostate cancer. Read more at OncLive.
the disease often recurs as aggressive castration-resistant prostate cancer (CRPC) with capacities of invasion and metastasis. The emergence of this aggressive phenotype involves a variety of mechanisms, especially the interaction between cancer cells and the tumor microenvironment [3]. Since the pejorat...