33 Detection of clinically significant prostate cancer by in-bore MRI-guided prostate biopsyObjective: This study aimed at evaluating linear discriminant analysis (LDA) and support vector machine (SVM) classifiers for estimating final Gleason score preoperatively using multiparametric magnetic resonance ...
32. Regulatory plexuses stem from chromatin interactions orchestrated by various factors including ZNF143, YY1, CTCF, and the cohesin complex34,35,36. Motivated by the oncogenic role of FOXA1 in prostate cancer, we investigated its regulatory plexus...
Prostate cancer is the second most common cause of male cancer deaths in the United States. However, the full range of prostate cancer genomic alterations is incompletely characterized. Here we present the complete sequence of seven primary human prostate cancers and their paired normal counterparts. ...
963 to 200 and Severe Pains Vanished.This is the story of a 72-year-old man from Surabaya, Indonesia. His prostate cancer had spread extensively to his back bone. I have the opportunity to meet with this patient in his house when we visited Surabaya. He benefited...
CHAPTER 33. Indigo—Cancer Relapse or Pelvic Node Disease Mark Scholz, MD CHAPTER 34. Unorthodox Therapies for Indigo Mark Scholz, MD CHAPTER 35. Minimizing the Side Effects of Chemotherapy Richard Lam, MD CHAPTER 36. Indigo—Situations in which PSA is Misleading ...
Prostate cancer (PCa) is one of the most commonly diagnosed human cancers in males. Nearly 191,930 new cases and 33,330 new deaths of PCa are estimated in 2020. Androgen and androgen receptor pathways played essential roles in the pathogenesis of PCa. Androgen depletion therapy is the most ...
Preirradiation hormonal cytoreduction of prostate cancer has been proven to reduce exposure of normal structures by decreasing the size of the target volume. Dose-volume histogram (DVH) analysis, however, does not always appear to demonstrate a strong positive benefit with the use of neoadjuvant horm...
The CACA Guidelines for Holistic Integrative Management of Prostate Cancer includes epidemiology, screening and diagnosis, treatment for localized PC, diagnosis and treatment of PC recurrence after radical prostatectomy, management of metastatic PC, traditional Chinese medicine diagnosis and treatment of PC,...
is another common alteration in prostate cancer pathogenesis and tends to co-occur after an ETS family fusion18,19. We therefore performed anti-ERG and anti-PTEN immunohistochemistry on serial sections of biopsy tissue (Fig.1c; Supplementary Fig.1c). The left-sided tumor was ERG-negative with...
(AACS) depletion is selectively lethal to malignant cells because the alternative route for Acetoacetate-CoA synthesis, Acetyl-CoA Acetyltransferase 2 (ACAT2) is selectively depleted in the tumor region (Fig.3A). ACAT2 is known to be down-regulated in prostate cancer33. This selective prediction ...