1.1.3Prostaglandin D2 synthase (PTGDS) or prostaglandin-H2 D-isomerase (HPGDS) Prostaglandin D synthase(PTGDS) or Prostaglandin-H2 D-isomerase (HPGDS) catalyzes the isomerization of the PGH precursor to PGD. Th
Prostaglandin-H2 D-isomerase (PTGDS), also designated as β-trace protein, is a 23- to 29-kDa secreted protein, which receives its name from the conversion of prostaglandin H2 into the isoform D2. From:Seminars in Nephrology,2018 Also in subject areas: ...
Martins-De-Souza D, Wobrock T, Zerr I, Schmitt A, Gawi- necka J, Schneider-Axmann T, Falkai P, Turck CW (2010) Different apolipoprotein E, apolipoprotein A1 and prostaglan- din-H2 D-isomerase levels in cerebrospinal fluid of schizo- phrenia patients and healthy controls. World J ...
Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. Biochim Biophys Acta 2005; 1743: 291–304. 31. Xiang Z, Lin T, Reeves SA. 15d-PGJ2 induces apoptosis of mouse oligodendrocyte precursor ...
IDI1 Isopentenyl-diphosphate delta isomerase 1 − 2.1 − 1.9 − 2.5 Steroid biosynthetic process ALOX5 Arachidonate 5-lipoxygenase − 2.2 − 2.1 − 3.1 Leukotriene metabolic process, inflammatory response SQLE Squalene epoxidase − 2.3 − 2.3 − 2.8 Sterol biosynthetic process CCL3 Che...
1.1.3 Prostaglandin D2 synthase (PTGDS) or prostaglandin-H2 D-isomerase (HPGDS) Prostaglandin D synthase (PTGDS) or Prostaglandin-H2 D-isomerase (HPGDS) catalyzes the isomerization of the PGH precursor to PGD. There are three types of PTGDS: the lipocalin-type PGDS (L-PTGDS) GSH independent,...
As a part of the prostanoid synthesis pathway, mPGES-1 catalyzes the conversion of prostaglandin (PG) H2, generated by COX, into PGE2, which represents a potent promotor of fever and inflammation. It is also the most efficient PGE syntheses in general. In the same line, mPGES-1 expressio...