Such compositions include a timolol component and a hypotensive lipid component. The present compositions and methods are relatively straightforward, can be easily produced, for example, using conventional manufacturing techniques, and can be easily and conveniently practiced, for example, using application...
In comparison with timolol Mt, the latanoprost/timolol FC led to a greater IOP reduction (MeD: -2.74, 95% CI: -3.24 to -2.23) than the bimatoprost/timolol FC (MeD: -1.49, 95% CI: -1.86 to -1.12) or the travoprost/timolol FC (MeD: -1.93, 95%CI: -2.98 to -0.88). The FCs ...
The effect on intraocular pressure (IOP) of adding prostaglandin F2 alpha-1-isopropyl ester (PGF2 alpha-IE) to timolol was studied in 21 eyes of 13 patients with newly diagnosed primary open-angle glaucoma that was inadequately controlled with timolol alone. After at least 2 weeks of twice dai...
Compositions of hypotensivem lipid (prostaglandin) and timolol, and their uses The present invention relates to a composition comprising timolol and a hypotensive lipid. The composition is useful as a medicine and in particular for the treatment of ocular hypertension. J Chen,D Woodward,A Kharlamb...
In normal volunteers, a single drop of unoprostone in one eye had no effect on IOP, blood pressure, heart rate, or pulsatile ocular blood flow.152On the other hand, timolol reduced IOP in both eyes (more in the treated eye) but also reduced pulsatile ocular blood flow, blood pressure,...
Watson PGStjernschantz JThe Latanoprost Study Group, A 6-month, randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. Ophthalmology. 1996;103126- 137Google ScholarCrossref 6. Wistrand PStjernschantz JOlsson K The incidence and time-course...
(isopropyl ester) Timolol maleate Active substance no 2 0.685 g PEG-15 hydroxystearate* Solubilizer and stabilizer 0.5 g Na2HPO4•12H2O Buffer 0.317 g NaH2PO4•2H2O Buffer 0.067 g Sorbitol Isotonicity agent 4.0 EDTA Antioxidant 0.05 g Purified water Vehicle qs 100 g *Solutol ® HS 15Exa...
In addition, for dual therapy approaches to treating an ocular condition, the method may include one or more additional steps of administering additional therapeutic agents to the eye, such as by topically administering compositions containing timolol, dorzolamide, and latoprost, among others. ...
Eyes were randomly assigned to receive topical aqueous suppressant (timolol-dorzolamide fixed combination), prostaglandin (PG) analogue (travoprost), or normal saline (control group). First, we observed the effects of topical eye drops on Tenon's tissue in non-operated eyes in rabbits. Second, ...
This review compared travoprost versus other prostaglandin analogues or timolol as treatments for open-angle glaucoma (OAG) or ocular hypertension (OH). Ov... pmhdev,PubMedHealth - Travoprost compared with other prostaglandin analogues or timolol in patients with open-angle glaucoma or ocular hyperten...