Bengtsson C: Comparison between metoprolol and propranolol as antihypertensive agents. A double-blind crossover study. Acta Med Scand 199: 71–74, 1976. View ArticleBengtsson, C. (1976). Comparison between metoprolol and propranolol as antihypertensive agents: a double-blind cross-over study. Acta...
Both propranolol and metoprolol are used for angina, and either is appropriate for most patients. The 2 drugs do have some differences, however, which may make 1 more appropriate than the other for a given patient. Propranolol is a nonselective agent, which means that it blocks beta receptors...
Pharmacokinetics of metoprolol, propranolol, and atenolol were investigated in six healthy volunteers following 7 days of oral monotherapy with these drugs, and after 7 days concurrent administration of each of these betareceptor antagonists with cimetidine. Application of cimetidine did not lead to any...
30. Horvath JS, Woolcock AJ, Tiller DJ, Donnelly P, Armstrong J, Caterson R (1978) "A comparison of metoprolol and propranolol on blood pressure and respiratory function in patients with hypertension."Aust N Z J Med, 8, p. 1-6 ...
The profiles of the following 10 beta blockers have been compared: acebutolol, atenolol, labetalol, metoprolol nadolol, oxprenolol, pindolol, propranolol, sotalol, and timolol Differences in the aromatic ring structure lead to ... Jurg,Meier - 《American Heart Journal》 被引量: 108发表: 19...
Experts recommend β-blocker therapy in all patients with left ventricular systolic dysfunction and prior MI; a β-blocker with proven mortality benefit (bisoprolol, carvedilol, or metoprolol succinate) is preferred. Although benefits of long-term β-blockade in patients with normal left ventricular ...
Propranolol, together with metoprolol, is one of the two β-blockers that are given the highest rating (level A) in practice AHS/AAN, CHS, and EFNS guidelines. It is highly lipophilic and therefore it can cross the blood-brain barrier. Compared to other β-blockers but similarly to metop...
Acebutolol has a significantly smaller effect on resting heart rate than propranolol, metoprolol and atenolol, although direct comparisons with drugs with intrinsic sympathomimetic activity have yet to be undertaken. In both angina and ... BN Singh,WR Thoden,A Ward - 《Drugs》 被引量: 5发表:...
The thermodynamic data from van't Hoff plots revealed that the enantioseparation was enthalpy driven for metoprolol and propranolol while entropy driven for atenolol. To understand the mechanism of chiral recognition and the elution behavior of the enantiomers, molecular docking studies were performed. ...
For propranolol and metoprolol, which undergo extensive presystemic clearance, the AUC values were lower (p<0.02) when the patients were hyperthyroid than when they had become euthyroid, but the t 1/2 's were not significantly altered. For atenolol, there were no significant kinetic differences ...