Summary: The effects on blood pressure and airway function of the chronic oral administration of two beta blocking agents, propranolol and metoprolol, were studied. Mean arterial pressure (MAP) fall was maximum with 160 mg of propranolol daily (-12 mmHg, P < 0 05) and 100 mg of metoprolol...
Floras JS, Jones JV, Hassan MO, Sleight P. Ambulatory blood pressure during once-daily randomised double-blind administration of atenolol, metoprolol, pindolol, and slow-release propranolol. British Medical Journal 285: 1387–1392, 1982 PubMedCASGoogle Scholar Floris B, Franchetta G, Palestini N...
Metoprolol also has a beneficial effect on monality when administered as early or late intervention therapy post-myocardial infarction as determined in the Goteborg. MIAMI and Stockholm clinical trials and by meta-analysis. The benefits of metoprolol in this selling may retlect anti-ischaemic and ant...
Other beta-blockers, such as bisoprolol (Zebeta), atenolol (Tenormin), or propranolol (Inderal LA, Innopran XL), which are medicines used for certain heart conditions or to reduce blood pressure Some other medicines may alter the blood levels of metoprolol/hydrochlorothiazide. Tell your healthca...
You should not use this medicine if you are allergic to metoprolol, or other beta-blockers (atenolol, carvedilol, labetalol, nadolol, nebivolol, propranolol, sotalol, and others), or if you have:a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate; severe ...
The antihypertensive effect of the new cardioselective prolonged-action beta-adrenoblocker bisoprolol compared with propranolol, metoprolol and placebo. Eksp Klin Farmakol 1995; 58: 32–34. 17 Kronig B. Influence of galenics on 24-h blood pressure control. Comparison of a new formulation of ...
Metoprolol (Lopressor, Toprol XL) is a prescription drug used to treat high blood pressure, angina, abnormal rhythms of the heart, and some neurological conditions. Drug interactions, dosage, and pregnancy and breastfeeding safety information are provide
(100–200 mg/day) compared with intravenous doses of 2.5 to 5 mg, titrated to effect. It is roughly half as potent as propranolol, and maximum β1-blockade effect is achieved at 0.2 mg/kg.Atenololis also β1selective, is lipophilic and has an elimination half-life of 6 hours...
Causes little inhibition of glycogenolysis in skeletal and cardiac muscles; inhibits increase in plasma glycerol during exercise; inhibits insulin release less than propranolol.Advice to PatientsImportance of taking metoprolol exactly as prescribed. Importance of not interrupting or discontinuing therapy withou...
In addition, TOPROL-XL administered at a dose of 50 mg once daily lowered blood pressure 24-hours post-dosing in placebo-controlled studies. In controlled, comparative, clinical studies, immediate-release metoprolol appeared comparable as an antihypertensive agent to propranolol, methyldopa, and ...