Prophylactic antibiotics cannot prevent ERCP-induced cholangitisZhaoShen Li
Antibiotics were prescribed for 62% of children who had surgery, and prophylaxis was the sole reason for antibiotic use in 73% of the patients. Prophylactic antibiotics were administered inappropriately with respect to timing or duration to 42% of the children receiving preoperative prophylaxis, 67%...
Bacteremia was detected by blood cultures (15- and 30-minute samples) in 4 patients who did not receive prophylactic antibiotics (Escherichia coli in 2 cases, Peptostreptococcus in 1, and Staphylococcus aureus in 1). Cholangitis or sepsis did not occur after the bacteremic episodes in any of ...
Antibiotics consume approximately 35% of the total pharmacy budget in most hospitals with betalactam antibiotics comprising almost 60% of all hospital uses (1). Expenditures on parenteral antibiotics have increased from $240 million in 1975 to over $1 billion in 1984. Antibiotic therapy and the as...
One hundred and eighty BA patients were recruited and randomized into a short-term (n = 90) and a long-term (n = 90) treatment group, and prophylactic intravenous antibiotics were used for 7 versus 14 days, respectively. The primary outcome was the overall cholangitis incidence within 6-...
Type and dose of antibiotics were not reported. Post-procedural infectious complications and AEs at 30-day follow-up were the main outcomes. Results AP was administered to 1,307 patients (81.4%). In this group, 3.4% of the patients had infectious complications compared to 3.7% in the non-...
recalcitrant cholangitisThe use of prophylactic antibiotics before endoscopic retrograde cholangiopancreatography (ERCP) is recommended by all major international gastroenterological societies, especially in the presence of an obstructed biliary system. This study compared the occurrence rate of post-procedural ...
Infection rates were compared by short (鈮 24?h), medium (>24 but 鈮 96?h), and long (>96?h) duration antibiotics. Multivariable regression analysis was performed to evaluate associations with a primary composite outcome of wound infection, organ-space infection, sepsis, or cholangitis. Among...
CONCLUSIONS : In suspected bile duct obstruction, incomplete drainage is a significant risk factor for post-ERCP cholangitis. Prophylactic antibiotics are not required provided a high success rate of adequate biliary drainage is achieved.doi:10.1016/S0016-5107(96)80130-1J. Vandervoort...
Given the concern for cholangitis, the patient was given antibiotics and three units of fresh frozen plasma (FFP) before biliary drain placement. After drain placement, and within 3h of receiving blood products, the patient became tachypnoeic and hypoxic with a chest X-ray revealing new ...