No randomized clinical trials have firmly established the duration of antibiotic therapy for the treatment of cholangitis. However, general guidelines are for antibiotic therapy to continue until biliary obstruction is completely relieved, biochemical liver function tests have improved or normalized, and the...
Antibiotic maintenance therapy can be highly successful in the treatment of recurrent cholangitis after resection of a malignancy at the hepatic hilum.doi:10.1007/BF01973995Springer-VerlagEuropean Journal of Clinical Microbiology & Infectious Diseases
Successful treatment of recurrent cholangitis complicating liver transplantation by Roux-en-Y limb lengthening. Transpl Infect Dis. 2007;9(4):327–31. Article CAS PubMed Google Scholar Orlando G, Blairvacq J-S, Otte J-B, Goffette P, Ciccarelli O, Sempoux C, et al. Successful treatment of...
Promising results have been reported for the role of antibiotic treatment in management of AC and PSC; however, immunosuppressive drugs have also rendered clinical responses in IAC. With respect to the high rate of complications, surgical interventions in patients with cholangitis are generally ...
recently showed that abrogation of intestinal microbial bile acid metabolism by antibiotic treatment induced depletion of intestinal microbiota and led to high hepatic synthesis of bile acids and successive biliary injury.146 This could be attenuated by farnesoid X receptor agonists. In cholestatic liver ...
The AASLD guidelines suggest[1]: PSC patients with recurrent bacterial cholangitis should be considered for long-term antibiotic therapy; and PSC patients with refractory bacterial cholangitis should be considered for liver transplantation. Overlap disorders between autoimmune hepatitis and PSC are more like...
performed in an urgent manner. Early correction of coagulation dysfunction was timely executed in patients with coagulopathy and/or ongoing anticoagulant therapy. All patients underwent furthermore medications in ICU, such as organ support, antibiotic therapy and close monitoring, after endoscopic ...
73 Therapy with tacrolimus (FK506), a macrolide antibiotic with immunosuppressive activity, improved pruritus and decreased serum bilirubin and alkaline phosphatase levels by over 50%. These patients, however, did not show a significant change in ERCP findings or histology.52 Immunosuppressants, ...
and prior instrumentation. The spectrum of the disease is highly variable from mild infection to systemic sepsis and shock. Management requires both medical and interventional strategies. Resuscitation with antibiotic therapy guided toward enteric pathogens and early biliary decompression is required. The fo...
is the most frequent underlying cause of cholangitis in Western countries. The management of cholangitis has evolved radically over the past century, moving from a purely surgical approach to an endoscopic one. Endoscopic retrograde cholangiopancreatography (ERCP) is currently the treatment of choice ...